Evidence map›Paper›PMID 29270467›Full record

SynthesisJACC. Clinical electrophysiology2017

Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review.

Lingjin Meng, Chi-Hong Tseng, Kalyanam Shivkumar, Olujimi Ajijola

3 registry-linked trialsAbstract readComparative StudySystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in JACC. Clinical electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 78 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04512911 early_phase1withdrawnnot on this mapstarted 2023, after this paper: background citation

Endocardial-Epicardial Radiofrequency Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2023Enrolled0ConditionsVentricular TachycardiaArmsEndocardial ablation, Endocardial- Epicardial ablation, Antiarrhythmic medications
NCT05656170 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Pre-Operative Stellate Ganglion to Prevent Post-Operative Atrial Fibrillation

TypeinterventionalSponsorRush University Medical CenterRan2023 to 2024Enrolled0ConditionsAtrial Fibrillation New OnsetArmsStellate ganglion block, Bupivacain, Saline
NCT05712122 nacompletednot on this mapstarted 2021, after this paper: background citation

Can Stellar Ganglion Blockage be an Alternative Treatment for Refractory Ventricular Arrhythmias?

TypeinterventionalSponsorAdana City Training and Research HospitalRan2021 to 2022Enrolled10ConditionsCardiac ArrhythmiaArmsstellate block
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Continuous stellate ganglion block for ventricular arrhythmias: case series, systematic review, and differences from thoracic epidural anaesthesia.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Cardioneuroablation for coronary artery vasospasm: a case report.European heart journal. Case reports · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Stellate ganglion block for refractory ventricular arrhythmias: an updated systematic review.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  19. Review
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lingjin MengUCLA Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, CA.
Chi-Hong TsengDivision of General Internal Medicine and Health Services Research, University of California, Los Angeles, CA.
Kalyanam ShivkumarUCLA Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, CA.
Olujimi AjijolaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, CA.

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
ELECTROPHYSIOLOGICAL EFFECTS OF NEURAL REMODELING OF THE VENTRICLESR01HL084261 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SHIVKUMAR, KALYANAM · 2006 to 2016
$3.4M
Multimodal Decoding of the Neural Circuitry of Sudden Death in Peripheral GangliaDP2HL142045 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A · 2017 to 2017
$2.3M
Antiarrhythmic Mechanisms of Bilateral Cardiac Sympathetic DecentralizationK08HL125730 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A · 2015 to 2019
$833k
NCATS NIH HHS UL1 TR001881NHLBI NIH HHS DP2 HL142045NHLBI NIH HHS K08 HL125730NHLBI NIH HHS R01 HL084261
6 · The paper itself

Abstract

backgroundThe efficacy of percutaneous stellate ganglion block (SGB) for managing electrical storm (ES) is not well understood.

objectiveTo characterize the efficacy of SGB as a treatment for ES.

methodsWe conducted literature searches using PubMed/Medline and Google Scholar, for mixed combinations of terms including "stellate ganglion block", *ganglion block (ade)", "sympathetic block (ade)" and "arrhythmia", "ventricular arrhythmia (VA)" or "tachycardia" (VT), "ventricular fibrillation" (VF), "electrical storm". Inclusion criteria were presentation with guideline-defined ES and treatment with SGB. Exclusion criteria: presentation with any supraventricular arrhythmia, VA without ES, or surgical sympathectomy. Studies lacking basic demographic data, arrhythmia description, and outcomes were excluded.

resultsOf 3,374 publications reviewed, 38 patients from 23 studies met study criteria (52 ± 19.1 years, 11 F, 17 with ischemic cardiomyopathy). Anti-arrhythmics were used in all patients. Mean Left ventricular ejection fraction was 31 ± 10%. ES was triggered by acute myocardial infarction in 15 patients and QT prolongation in 7 patients. The most common local anesthetic used for SGB was bupivacaine (0.25-0.5%). SGB resulted in a significant decrease in VA burden (12.4±8.8 vs. 1.04±2.12 episodes/day, p< 0.001) and number of external and ICD shocks (10.0±9.1 vs. 0.05±0.22 shocks/day, p< 0.01). Following SGB, 80.6% of patients survived to discharge.

conclusionSGB is an effective acute treatment for ES. However, larger prospective randomized studies are needed to better understand the role of SGB in ES and other VAs.

Indexed as

AdultAgedAnesthetics, LocalAutonomic Nerve BlockBupivacaineFemaleHumansMaleMiddle AgedRetrospective StudiesStellate GanglionTachycardia, VentricularUltrasonography, InterventionalVentricular FibrillationAnesthetics, LocalBupivacaineautonomic nervous systemelectrical stormneuromodulationStellate ganglion blocksympathetic nerves

Identifiers

PMID29270467
PMCPMC5734652

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.