Evidence map›Paper›PMID 29270391›Full record

ArticleFrontiers in cellular and infection microbiology2017

Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome.

Kristi Biswas, Brett Wagner Mackenzie, Sharon Waldvogel-Thurlow, Martin Middleditch, Mia Jullig, Melissa Zoing, Michael W Taylor, Richard G Douglas

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  7. Effect ofAllergy, asthma & immunology research · 2021
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  16. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristi BiswasDepartment of Surgery, School of Medicine, University of Auckland, Auckland, New Zealand.
Brett Wagner MackenzieDepartment of Surgery, School of Medicine, University of Auckland, Auckland, New Zealand.
Sharon Waldvogel-ThurlowDepartment of Surgery, School of Medicine, University of Auckland, Auckland, New Zealand.
Martin MiddleditchSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Mia JulligAuckland Science Analytical Services, University of Auckland, Auckland, New Zealand.
Melissa ZoingDepartment of Surgery, School of Medicine, University of Auckland, Auckland, New Zealand.
Michael W TaylorSchool of Biological Sciences, University of Auckland, Auckland, New Zealand.
Richard G DouglasDepartment of Surgery, School of Medicine, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chronic inflammatory nature of chronic rhinosinusitis (CRS) makes it a morbid condition for individuals with the disease and one whose pathogenesis is poorly understood. To date, proteomic approaches have been applied successfully in a handful of CRS studies. In this study we use a multifaceted approach, including proteomics (iTRAQ labeling) and microbiome (bacterial 16S rRNA gene sequencing) analyses of middle meatus swabs, as well as immune cell analysis of the underlying tissue, to investigate the host-microbe interaction in individuals with CRS (

Indexed as

Host-Pathogen InteractionsMicrobiotaAdultAgedB-LymphocytesChronic DiseaseCluster AnalysisDNA, BacterialDNA, RibosomalFemaleHumansMacrophagesMaleMiddle AgedPhylogenyProteomeDNA, BacterialDNA, RibosomalProteomeRNA, Ribosomal, 16Sbacterial 16S rRNA genebiomarkersinflammatory cellsproteomicsPRRC2CRAB14

Identifiers

PMID29270391
PMCPMC5723659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.