ArticleCurrent oncology (Toronto, Ont.)2017
The OncoSim model: development and use for better decision-making in Canadian cancer control.
Article in Current oncology (Toronto, Ont.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cost-effectiveness models of non-small cell lung cancer: A systematic literature review.Journal of managed care & specialty pharmacy · 2025Pooled it
- Supplemental Screening as an Adjunct to Mammography for Breast Cancer Screening in People With Dense Breasts: A Health Technology Assessment.Ontario health technology assessment series · 2023Pooled it
- Simulation modeling validity and utility in colorectal cancer screening delivery: A systematic review.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Enhancing the OncoSim-Breast model using Canadian breast density information.Health reports · 2026Article
- Should we screen for colorectal cancer with biennial FIT beginning at age 45 in Canada?Journal of the Canadian Association of Gastroenterology · 2026Article
- The projected health and economic impact of increased colorectal cancer screening participation among Canadians by income quintile.Canadian journal of public health = Revue canadienne de sante publique · 2024Article
- Efficient organized colorectal cancer screening in Shenzhen: a microsimulation modelling study.BMC public health · 2024Article
- Exploring the Future of Cancer Impact in Alberta: Projections and Trends 2020-2040.Current oncology (Toronto, Ont.) · 2023Article
- The OncoSim-Breast Cancer Microsimulation Model.Current oncology (Toronto, Ont.) · 2022Article
- Projected Impact of Weight Gain During the COVID-19 Pandemic on the Future Burden of Cancer in Canada.Frontiers in oncology · 2022Article
- Estimating the future cancer management costs attributable to modifiable risk factors in Canada.Canadian journal of public health = Revue canadienne de sante publique · 2021Article
- Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I).Journal of personalized medicine · 2021Article
- The EU-TOPIA evaluation tool: An online modelling-based tool for informing breast, cervical, and colorectal cancer screening decisions in Europe.Preventive medicine reports · 2021Article
- The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada.Journal of medical screening · 2021Article
- The Value of All-Cause Mortality as a Metric for Assessing Breast Cancer Screening.Journal of the National Cancer Institute · 2020Article
- Use of Simulation Modeling to Inform Decision Making for Health Care Systems and Policy in Colorectal Cancer Screening: Protocol for a Systematic Review.JMIR research protocols · 2020Article
- Moving toward the elimination of cervical cancer: modelling the health and economic benefits of increasing uptake of human papillomavirus vaccines.Current oncology (Toronto, Ont.) · 2019Article
- Predicting the Epidemiological Dynamics of Lung Cancer in Japan.Journal of clinical medicine · 2019Article
- This is a call to oncologists for action.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018Review
- Simulation modeling to assist with childhood obesity control: perceptions of Baltimore City policymakers.Journal of public health policy · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Canadian Partnership Against Cancer was created in 2007 by the federal government to accelerate cancer control across Canada. Its OncoSim microsimulation model platform, which consists of a suite of specific cancer models, was conceived as a tool to augment conventional resources for population-level policy- and decision-making. The Canadian Partnership Against Cancer manages the OncoSim program, with funding from Health Canada and model development by Statistics Canada. Microsimulation modelling allows for the detailed capture of population heterogeneity and health and demographic history over time. Extensive data from multiple Canadian sources were used as inputs or to validate the model. OncoSim has been validated through expert consultation; assessments of face validity, internal validity, and external validity; and model fit against observed data. The platform comprises three in-depth cancer models (lung, colorectal, cervical), with another in-depth model (breast) and a generalized model (25 cancers) being in development. Unique among models of its class, OncoSim is available online for public sector use free of charge. Users can customize input values and output display, and extensive user support is provided. OncoSim has been used to support decision-making at the national and jurisdictional levels. Although simulation studies are generally not included in hierarchies of evidence, they are integral to informing cancer control policy when clinical studies are not feasible. OncoSim can evaluate complex intervention scenarios for multiple cancers. Canadian decision-makers thus have a powerful tool to assess the costs, benefits, cost-effectiveness, and budgetary effects of cancer control interventions when faced with difficult choices for improvements in population health and resource allocation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.