Evidence map›Paper›PMID 29269886›Full record

ArticleScientific reports2017

Non-invasive multimodal optical coherence and photoacoustic tomography for human skin imaging.

Zhe Chen, Elisabet Rank, Kristen M Meiburger, Christoph Sinz, Andreas Hodul, Edward Zhang, Erich Hoover, Micheal Minneman, Jason Ensher, Paul C Beard and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Zhe ChenCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria.
Elisabet RankCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria.
Kristen M MeiburgerDipartimento di Elettronica e Telecomunicazioni, Biolab, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Christoph SinzDepartment of Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, AKH 7J, 1090, Vienna, Austria.
Andreas HodulCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria.
Edward ZhangDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, WC1E 6BT, London, UK.
Erich HooverInsight Photonic Solutions, Inc., 2650 Crescent Drive, Number 201, Lafayette, CO, 80026, USA.
Micheal MinnemanInsight Photonic Solutions, Inc., 2650 Crescent Drive, Number 201, Lafayette, CO, 80026, USA.
Jason EnsherInsight Photonic Solutions, Inc., 2650 Crescent Drive, Number 201, Lafayette, CO, 80026, USA.
Paul C BeardDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, WC1E 6BT, London, UK.
Harald KittlerDepartment of Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, AKH 7J, 1090, Vienna, Austria.
Rainer A LeitgebCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria.
Wolfgang DrexlerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria.
Mengyang LiuCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, AKH 4L, 1090, Vienna, Austria. mengyang.liu@meduniwien.ac.at.ORCID 0000-0002-8862-5966
Medical University of Vienna · ATPhotonic Systems (United States) · USUniversity College London · GBPolitecnico di Torino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cutaneous vasculature is involved in many diseases. Current clinical examination techniques, however, cannot resolve the human vasculature with all plexus in a non-invasive manner. By combining an optical coherence tomography system with angiography extension and an all optical photoacoustic tomography system, we can resolve in 3D the blood vessels in human skin for all plexus non-invasively. With a customized imaging unit that permits access to various parts of patients' bodies, we applied our multimodality imaging system to investigate several different types of skin conditions. Quantitative vascular analysis is given for each of the dermatological conditions to show the potential diagnostic value of our system in non-invasive examination of diseases and physiological processes. Improved performance of our system over its previous generation is also demonstrated with an updated characterization.

Indexed as

HumansImaging, Three-DimensionalPhotoacoustic TechniquesSkinTomography, Optical Coherence

Identifiers

PMID29269886
PMCPMC5740114
OpenAlexW2775179058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.