Evidence map›Paper›PMID 29269351›Full record

SynthesisJournal of the American Heart Association2017

Reduction of Arterial Stiffness After Kidney Transplantation: A Systematic Review and Meta-Analysis.

Aboubacar Sidibé, Catherine Fortier, Marie-Pier Desjardins, Hervé Tchala Vignon Zomahoun, Amélie Boutin, Fabrice Mac-Way, Sacha De Serres, Mohsen Agharazii

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Salutary Blood Pressure of a Solitary Kidney.American journal of hypertension · 2020
    Article
  12. Article
  13. Arterial Stiffness in the Heart Disease of CKD.Journal of the American Society of Nephrology : JASN · 2019
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aboubacar SidibéCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada.
Catherine FortierCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada.
Marie-Pier DesjardinsCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada.
Hervé Tchala Vignon ZomahounCHU de Québec Research Center, Université Laval Saint François d'Assise Hospital, Québec, Canada.
Amélie BoutinDepartment of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Québec, Canada.
Fabrice Mac-WayCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada.
Sacha De SerresCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada.
Mohsen AgharaziiCHU de Québec Research Center, L'Hôtel-Dieu de Québec Hospital, Québec, Canada Mohsen.Agharazii@crchudequebec.ulaval.ca.
Hôtel-Dieu de Québec · CAUniversité Laval · CA

Funding

CIHR
6 · The paper itself

Abstract

backgroundEnd-stage kidney disease is associated with increased arterial stiffness. Although correction of uremia by kidney transplantation (KTx) could improve arterial stiffness, results from clinical studies are unclear partly due to small sample sizes. METHOD AND

resultsWe conducted a systematic review and meta-analysis of before-after design studies performed in adult KTx patients with available measures of arterial stiffness parameters (pulse wave velocity [PWV], central pulse pressure [PP], and augmentation index) before and at any time post-KTx. Mean difference of post- and pre-KTx values of different outcomes were estimated using a random effect model with 95% confidence interval. To deal with repetition of measurement within a study, only 1 period of measurement was considered per study by analysis. Twelve studies were included in meta-analysis, where a significant decrease of overall PWV by 1.20 m/s (95% CI 0.67-1.73, I

conclusionsThis meta-analysis suggests a reduction of the overall arterial stiffness in patients with end-stage kidney disease after KTx.

Indexed as

Kidney TransplantationBrachial ArteryHumansKidney Failure, ChronicPostoperative PeriodPulse Wave AnalysisVascular Stiffnessarterial stiffnessaugmentation indexkidneypulse pressurepulse wave velocitytransplantation

Identifiers

PMID29269351
PMCPMC5779037
OpenAlexW2778471324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.