Evidence map›Paper›PMID 29268916›Full record

GuidelineJournal of vascular surgery2018

The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm.

Elliot L Chaikof, Ronald L Dalman, Mark K Eskandari, Benjamin M Jackson, W Anthony Lee, M Ashraf Mansour, Tara M Mastracci, Matthew Mell, M Hassan Murad, Louis L Nguyen and 4 more

14 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Journal of vascular surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 14 registered trials, which are not on this map. Cited by 890 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
890citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04252079 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Endovascular Repair of Juxtarenal Aortic Aneurysm

TypeinterventionalSponsorAssiut UniversityRan2020 to 2021Enrolled30ConditionsJuxtarenal Aortic AneurysmArmsEndovascular Repair of Juxtarenal Aortic Aneurysm
NCT04269447 enrolling by invitationnot on this mapstarted 2019, after this paper: background citation

POP-STAR: The Prospective Data Collection on Patients With Abdominal Aortic Aneurysms at the Stockholm Aneurysm Research Group (STAR)

Typeobservational_patient_registrySponsorKarolinska University HospitalRan2019 to 2028Enrolled400ConditionsAbdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured, Aortic Aneurysm, Aneurysm AbdominalArmsStructured imaging follow-up
NCT04532450 completednot on this map

Outcomes of Fenestrated and Branched Stent Grafts to Treat Secondary Type 1 Endoleak After Endovascular Aneurysm Repair : A Prospective Multicentre Study

TypeobservationalSponsorUniversity Paul Sabatier of ToulouseRan2010 to 2019Enrolled85ConditionsAbdominal Aortic AneurysmArmsBranched / fenestrated aortic stent graft
NCT05150873 completednot on this mapstarted 2022, after this paper: background citation

Anatomical Feasibility of an Off-the-shelf Scalloped Stent-graft for Infrarenal Abdominal Aneurysm With a Hostile Neck (ReSTHoNe Study)

TypeobservationalSponsorAzienda Ospedaliero-Universitaria di ModenaRan2022 to 2022Enrolled1,000ConditionsAortic AneurysmArmsCTA evaluation
NCT05287828 completednot on this mapstarted 2022, after this paper: background citation

Retrospective Study for the Validation of an Automatic Software for Geometric Measurements of the Principal Arteries and Calcification Detection on Patients With Aortic Aneurysm.

TypeobservationalSponsorNureaRan2022 to 2023Enrolled65ConditionsAortic AneurysmArmsSurgeons CT scan analysis, PRAEVAorta CT scan analysis
NCT05346289 completednot on this mapstarted 2020, after this paper: background citation

Elective Treatment Rates Among Patients With Intact Abdominal Aortic Aneurysms -Patient- and Aneurysm-related Factors as Determinants of Surgical Non-eligibility in Women and Men

TypeobservationalSponsorKarolinska University HospitalRan2020 to 2022Enrolled400ConditionsAbdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Aneurysm, Aortic AneurysmArmsElective surgery for intact AAA
NCT05360108 active not recruitingnot on this mapstarted 2020, after this paper: background citation

Screening for Abdominal Aortic Aneurysm and Popliteal Artery Aneurysm in At-risk Population (DAAP-PR Study)

TypeobservationalSponsorCentre Hospitalier Universitaire VaudoisRan2020 to 2029Enrolled507ConditionsAortic Aneurysm, Abdominal, Popliteal Artery Aneurysm
NCT05607277 completednot on this map

Global Iliac Branch Study (Iliac Conformability Paper, Gore vs. Cook)

TypeobservationalSponsorUniversity of Wisconsin, MadisonRan2014 to 2021Enrolled297ConditionsAbdominal Aortic Aneurysm, Iliac AneurysmArmsEndovascular Repair of abdominal aortic aneurysms
NCT05609539 completednot on this mapstarted 2023, after this paper: background citation

Clinical Effectiveness of an Off-the-shelf Single REnal Scalloped sTent-graft for HOstile NEck Infrarenal Abdominal Aortic Aneurysm: Clinical Pivotal Trial

TypeobservationalSponsorAzienda Ospedaliero-Universitaria di ModenaRan2023 to 2025Enrolled50ConditionsAbdominal Aortic AneurysmArmsEndovascular Aortic Repair (EVAR)
NCT05920317 unknown statusnot on this mapstarted 2023, after this paper: background citation

Retrospective Study of the Use of PRAEVAorta 2 Software for Vessel Geometric Analysis Versus Standard Analysis Methods in Patients With Abdominal Aortic Aneurysm

TypeobservationalSponsorNureaRan2023 to 2023Enrolled50ConditionsAbdominal Aortic Aneurysm
NCT06566976 narecruitingnot on this mapstarted 2024, after this paper: background citation

Prehabilitation and Rehabilitation in PAD: A Randomized Exercise Intervention Trial (PREPARE-IT)

TypeinterventionalSponsorPalo Alto Veterans Institute for ResearchRan2024 to 2027Enrolled300ConditionsPeripheral Arterial DiseaseArmsExercise Intervention, VAPAHCS Rehabilitation Core Components
NCT06570785 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Contralateral Limb Cannulation Using Intra-Operative Positioning SystemTechnology in Endovascular Aneurysm Repair

TypeobservationalSponsorClinical Centre of SerbiaRan2025 to 2025Enrolled80ConditionsAbdominal Aortic Aneurysm, Abdominal Aortic Aneurysm Without Rupture, Radiation ExposureArmsIntra-Operative Positioning System (IOPS), Conventional group
NCT07431047 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Fast-Track Protocol for Infrarenal EVAR

Typeobservational_patient_registrySponsorUniversity of BolognaRan2026 to 2027Enrolled50ConditionsAbdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Iliac Aneurysm
NCT07783126 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Deep-learning Prediction of Abdominal Aortic Aneurysm Enlargement in Type II Endoleak After EVAR: Development and Multicenter Validation of an End-to-end Deep-learning Model (the RADAR Study)

TypeobservationalSponsorEnte Ospedaliero Cantonale, BellinzonaRan2026 to 2028Enrolled1,250ConditionsType II Endoleak, Abdominal Aortic Aneurysm EnlargementArmsArtificial intelligence model analyzing preoperative CT angiography
3 · Its place in the literature

Who cites it

890 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  6. Intensive care after vascular surgery: systematic review.The British journal of surgery · 2025
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830 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Elliot L ChaikofDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, Mass. Electronic address: echaikof@bidmc.harvard.edu.
Ronald L DalmanDepartment of Surgery, Stanford University, Palo Alto, Calif.
Mark K EskandariDepartment of Surgery, Northwestern University, Chicago, Ill.
Benjamin M JacksonDepartment of Surgery, University of Pennsylvania, Philadelphia, Pa.
W Anthony LeeChristine E. Lynn Heart & Vascular Institute, Boca Raton Regional Hospital, Boca Raton, Fla.
M Ashraf MansourDepartment of Surgery, Spectrum Health Medical Group, Grand Rapids, Mich.
Tara M MastracciThe Royal Free Hospital, London, United Kingdom.
Matthew MellDepartment of Surgery, Stanford University, Palo Alto, Calif.
M Hassan MuradEvidence-based Practice Center, Mayo Clinic, Rochester, Minn.
Louis L NguyenDepartment of Surgery, Brigham and Women's Hospital, Boston, Mass.
Gustavo S OderichDepartment of Surgery, Mayo Clinic, Rochester, Minn.
Madhukar S PatelDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, Mass; Department of Surgery, Massachusetts General Hospital, Boston, Mass.
Marc L SchermerhornDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, Mass.
Benjamin W StarnesDepartment of Surgery, University of Washington, Seattle, Wash.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecision-making related to the care of patients with an abdominal aortic aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient-specific factors influence anticipated life expectancy, operative risk, and need to intervene. Careful attention to the choice of operative strategy along with optimal treatment of medical comorbidities is critical to achieving excellent outcomes. Moreover, appropriate postoperative surveillance is necessary to minimize subsequent aneurysm-related death or morbidity.

methodsThe committee made specific practice recommendations using the Grading of Recommendations Assessment, Development, and Evaluation system. Three systematic reviews were conducted to support this guideline. Two focused on evaluating the best modalities and optimal frequency for surveillance after endovascular aneurysm repair (EVAR). A third focused on identifying the best available evidence on the diagnosis and management of AAA. Specific areas of focus included (1) general approach to the patient, (2) treatment of the patient with an AAA, (3) anesthetic considerations and perioperative management, (4) postoperative and long-term management, and (5) cost and economic considerations.

resultsAlong with providing guidance regarding the management of patients throughout the continuum of care, we have revised a number of prior recommendations and addressed a number of new areas of significance. New guidelines are provided for the surveillance of patients with an AAA, including recommended surveillance imaging at 12-month intervals for patients with an AAA of 4.0 to 4.9 cm in diameter. We recommend endovascular repair as the preferred method of treatment for ruptured aneurysms. Incorporating knowledge gained through the Vascular Quality Initiative and other regional quality collaboratives, we suggest that the Vascular Quality Initiative mortality risk score be used for mutual decision-making with patients considering aneurysm repair. We also suggest that elective EVAR be limited to hospitals with a documented mortality and conversion rate to open surgical repair of 2% or less and that perform at least 10 EVAR cases each year. We also suggest that elective open aneurysm repair be limited to hospitals with a documented mortality of 5% or less and that perform at least 10 open aortic operations of any type each year. To encourage the development of effective systems of care that would lead to improved outcomes for those patients undergoing emergent repair, we suggest a door-to-intervention time of <90 minutes, based on a framework of 30-30-30 minutes, for the management of the patient with a ruptured aneurysm. We recommend treatment of type I and III endoleaks as well as of type II endoleaks with aneurysm expansion but recommend continued surveillance of type II endoleaks not associated with aneurysm expansion. Whereas antibiotic prophylaxis is recommended for patients with an aortic prosthesis before any dental procedure involving the manipulation of the gingival or periapical region of teeth or perforation of the oral mucosa, antibiotic prophylaxis is not recommended before respiratory tract procedures, gastrointestinal or genitourinary procedures, and dermatologic or musculoskeletal procedures unless the potential for infection exists or the patient is immunocompromised. Increased utilization of color duplex ultrasound is suggested for postoperative surveillance after EVAR in the absence of endoleak or aneurysm expansion.

conclusionsImportant new recommendations are provided for the care of patients with an AAA, including suggestions to improve mutual decision-making between the treating physician and the patients and their families as well as a number of new strategies to enhance perioperative outcomes for patients undergoing elective and emergent repair. Areas of uncertainty are highlighted that would benefit from further investigation in addition to existing limitations in diagnostic tests, pharmacologic agents, intraoperative tools, and devices.

Indexed as

Antibiotic ProphylaxisAortic Aneurysm, AbdominalBiomarkersBlood Vessel ProsthesisClinical Decision-MakingElective Surgical ProceduresEndoleakEndovascular ProceduresHumansPerioperative CarePreoperative CareRisk AssessmentRisk FactorsSocieties, MedicalSpecialties, SurgicalTime FactorsBiomarkers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 8 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.