Evidence map›Paper›PMID 29268784›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2017

Amir Iravani, Michael S Hofman, Tony Mulcahy, Scott Williams, Declan Murphy, Bimal K Parameswaran, Rodney J Hicks

Open access · goldAbstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Comparative Analysis ofAdvances in radiation oncology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Appropriate Use Criteria for Prostate-Specific Membrane Antigen PET Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  10. Prospective intra-individual blinded comparison of [European journal of nuclear medicine and molecular imaging · 2022
    Article
  11. Intra-patient comparison of physiologicCancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  12. Article
  13. The utility of pharmacological and radiological interventions to optimize diagnostic information from PET/CT.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Review
  14. Article
  15. Review
  16. Intra-individual comparison ofCancer imaging : the official publication of the International Cancer Imaging Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amir IravaniCentre for Molecular Imaging, Department of Cancer Imaging, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Australia. amir.iravani@petermac.org.ORCID http://orcid.org/0000-0002-1273-5835
Michael S HofmanCentre for Molecular Imaging, Department of Cancer Imaging, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Australia.
Tony MulcahyCentre for Molecular Imaging, Department of Cancer Imaging, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Australia.
Scott WilliamsSir Peter MacCallum Department of Radiation Oncology, University of Melbourne, 305 Grattan Street, Melbourne, Australia.
Declan MurphySir Peter MacCallum Department of Surgical Oncology, University of Melbourne, 305 Grattan Street, Melbourne, Australia.
Bimal K ParameswaranCentre for Molecular Imaging, Department of Cancer Imaging, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Australia.
Rodney J HicksCentre for Molecular Imaging, Department of Cancer Imaging, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Australia.
The University of Melbourne · AUPeter MacCallum Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsA retrospective review of PSMA PET/CT-U preformed on 57 consecutive patients with prostate cancer. Fifty mL of IV contrast was administered 10 min (range 8-15) before the CT component of a combined PET/CT study, acquired approximately 60 min (range 40-85) after administration of 166 MBq (range 91-246) of

resultsOverall 50 PSMA PET/CT-U studies were performed for BCR and 7 for PS. Median PSA with BCR and PS were 2.0 ± 11.4 ng/ml (0.06-57.3 ng/ml) and 18 ± 35.3 ng/ml (6.8-100 ng/ml), respectively. The median Gleason-score for both groups was 7 (range 6-10). In BCR group, PSMA PET was reported positive in 36 (72%) patients, CT-U in 11(22%) patients and PET/CT-U in 33 (66%) patients. In PS group, PSMA PET detected the primary site in all seven patients, of which one patient with metastatic nodal disease had negative CT finding. Of 40 equivocal foci (27/57 patients) on PET, 11 foci (10/57 patients, 17.5%) were localized to enhanced urine on PET/CT-U, hence considered of potential benefit in interpretation. Of those, 3 foci (3 patients) were solitary sites of activity on PSMA imaging including two local and one nodal site and 4 foci (3 patients) were in different nodal fields.

conclusionsPET/CT-U protocol is a practical approach and may assist in interpretation of

Indexed as

Positron Emission Tomography Computed TomographyUrographyAgedEdetic AcidGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedNeoplasm GradingOligopeptidesProstatic NeoplasmsRadiopharmaceuticalsEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptidesRadiopharmaceuticals68Ga-PSMA-11 PETBiochemical recurrenceCT urogramProstate cancerPSMA-HBED PETPSMA PET/CT

Identifiers

PMID29268784
PMCPMC5740783
OpenAlexW2777621720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.