Evidence map›Paper›PMID 29268748›Full record

ArticleBMC musculoskeletal disorders2017

Patient and surgical factors affecting procedure duration and revision risk due to deep infection in primary total knee arthroplasty.

Mona Badawy, Birgitte Espehaug, Anne Marie Fenstad, Kari Indrekvam, Håvard Dale, Leif I Havelin, Ove Furnes

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Hospital volume-outcome relationship in total knee arthroplasty: a systematic review and dose-response meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona BadawyCoastal Hospital in Hagavik, 5217, Hagavik, Norway. mona.badawy@helse-bergen.no.
Birgitte EspehaugCenter for Evidence-based Practice, Bergen University College, 5021, Bergen, Norway.
Anne Marie FenstadThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, 5021, Bergen, Norway.
Kari IndrekvamCoastal Hospital in Hagavik, 5217, Hagavik, Norway.
Håvard DaleDepartment of Clinical Medicine, Institute of Medicine and Dentistry, University of Bergen, 5021, Bergen, Norway.
Leif I HavelinThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, 5021, Bergen, Norway.
Ove FurnesThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, 5021, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess which patient and procedure factors affected both the risk of infection as well as procedure duration. Additionally, to assess if procedure duration affected the revision risk due to deep infection in total knee arthroplasty (TKA) patients and in a subgroup of low-risk patients.

methods28,262 primary TKA with 311 revisions due to deep infection were included from the Norwegian Arthroplasty Register (NAR) and analysed from primary surgery from 2005 until 31st December 2015 with a 1 and 4 year follow up. The risk of revision due to deep infection was calculated in a multivariable Cox regression model including patient and procedure related risk factors, assessing Hazard Ratio (HR) with 95% confidence interval (CI).

resultsMultivariate analysis showed statistically significant associations with revision due to deep infection and increased procedure duration for male patients, ASA3+ (American Society of Anesthesiologists) and perioperative complications. Procedure duration ≥110 min (75 percentile) had a higher risk of deep infection compared to duration <75 min (25 percentile), in the unadjusted analysis (HR = 1.8, 95% CI 1.3-2.5, p = 0.001) and in the adjusted analysis (HR = 1.5, 95% CI 1.0-2.1, p = 0.03). For low-risk patients, procedure duration did not increase the risk of infection.

conclusionMale patients, ASA 3+ patients and perioperative complications were risk factors both for longer procedure duration and for deep infection revisions. Patients with a high degree of comorbidity, defined as ASA3+, are at risk of infection with longer procedure durations. The occurrence of perioperative complications potentially leading to a more complex and lengthy procedure was associated with a higher risk of infection. Long procedure duration in itself seems to have minor impact on infection since we found no association in the low-risk patient.

Indexed as

Operative TimeAgedAged, 80 and overArthroplasty, Replacement, KneeFemaleFollow-Up StudiesHumansMaleMiddle AgedPreoperative CareProsthesis FailureProsthesis-Related InfectionsReoperationRetrospective StudiesRisk FactorsArthroplastyInfectionKneeOsteoarthritisProcedure durationRevisionRisk factors

Identifiers

PMID29268748
PMCPMC5740908

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.