Evidence map›Paper›PMID 29268535›Full record

ReviewJournal of thoracic disease2017

Persistent air leaks: a review with an emphasis on bronchoscopic management.

Donald R Lazarus, Roberto F Casal

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07184528 (PATCHVALVE Trial), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07184528 narecruitingnot on this mapstarted 2025, after this paper: background citation

PATCHVALVE Trial: A Prospective Evaluation of Blood Patch and Endobronchial Valves for Persistent Air Leaks - Pilot Study

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2025 to 2027Enrolled20ConditionsPersistent Air LeaksArmsEndobronchial Blood Patch, Spiration Valve System (SVS) Placement
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 90 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. An unintended path, an unusual solution.Breathe (Sheffield, England) · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A Comparison of the Efficacies of OK-432 and Talc Slurry for Pleurodesis in Patients with Prolonged Air Leak after Pulmonary Resection.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Air leaks in COVID-19.World journal of virology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Donald R LazarusDepartment of Pulmonary, Critical Care, and Sleep Section, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, USA.
Roberto F CasalDepartment of Pulmonary Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
Michael E. DeBakey VA Medical Center · USThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent air leak (PAL) is a cause of significant morbidity in patients who have undergone lung surgery and those with significant parenchymal lung disease suffering from a pneumothorax. Its management can be complex and challenging. Although conservative treatment with chest drain and observation is usually effective, other invasive techniques are needed when conservative treatment fails. Surgical management and medical pleurodesis have long been the usual treatments for PAL. More recently numerous bronchoscopic procedures have been introduced to treat PAL in those patients who are poor candidates for surgery or who decline surgery. These techniques include bronchoscopic use of sealants, sclerosants, and various types of implanted devices. Recently, removable one-way valves have been developed that are able to be placed bronchoscopically in the affected airways, ameliorating air-leaks in patients who are not candidates for surgery. Future comparative trials are needed to refine our understanding of the indications, effectiveness, and complications of bronchoscopic techniques for treating PAL. The following article will review the basic principles of management of PAL particularly focusing on bronchoscopic techniques.

Indexed as

alveolar-pleural fistulabronchopleural fistula (BPF)intrabronchial valves (IBVs)Persistent air leak (PAL)pleurodesis

Identifiers

PMID29268535
PMCPMC5720990
OpenAlexW2767587810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.