ArticleJournal of thoracic disease2017
Reference values for spirometry in Chinese aged 4-80 years.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic Accuracy of FEFLung · 2025Pooled it
- Development and validation of nomogram including high altitude as a risk factor for COPD: A cross-sectional study based on Gansu population.Frontiers in public health · 2023Trial
- Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4-17 years.Respiratory research · 2022Trial
- Applicability of the Global Lung Initiative 2022 Reference Equations on a Sample of Healthy Adolescents in Jordan.Children (Basel, Switzerland) · 2026Article
- Incidence of acute exacerbation and its related factors among chronic obstructive pulmonary disease patients aged 40 years and older in China.Chinese medical journal pulmonary and critical care medicine · 2026Article
- Impact of bronchodilator responsiveness on lung age in patients with respiratory diseases and/or symptoms: implications for clinical practice from a cross-sectional study.Journal of thoracic disease · 2026Article
- Exposure-response relationship between ambient PMFrontiers in public health · 2026Article
- Associations of spirometricFrontiers in public health · 2026Article
- Comparative analysis of pulmonary function in diverse ethnic adults living at low and high altitudes.Respiratory research · 2025Observational
- An association of Mycoplasma pneumonia with lung function and laboratory parameters.Scientific reports · 2025Article
- Tiotropium in Patients With Airflow Limitation According to the Fixed Ratio But Not the Lower Limit of Normal: A Secondary Analysis of the Tiotropium in Early-COPD Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Anomalous Differences Between the Global Lung Function Initiative 2023 and 2012 Spirometry Reference Values.Chest · 2025Article
- Boosting K-nearest neighbor regression performance for longitudinal data through a novel learning approach.BMC bioinformatics · 2025Article
- The association between lung function and sensory impairments among chinese middle-aged and older adults: a longitudinal cohort study from CHARLS.NPJ primary care respiratory medicine · 2025Article
- The relationship between lung function and headache risk in middle-aged and older adults: a cross-sectional and longitudinal study.European journal of medical research · 2025Article
- Reference equations for pulmonary function testing in healthy Chinese children aged 4-18 years.Respiratory research · 2025Article
- Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation parameters: an observational study.BMC medical informatics and decision making · 2025Observational
- Lung function decline and incidence of chronic obstructive pulmonary disease in participants with spirometry-defined small airway dysfunction: a 15-year prospective cohort study in China.Respiratory research · 2025Article
- Article
- Machine learning-based spirometry reference values for the Iranian population: a cross-sectional study from the Shahedieh PERSIAN cohort.Frontiers in medicine · 2025Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough there are over 1.34 billion Chinese in the world, nationwide spirometric reference values for Chinese are unavailable, which is usually based on Caucasian conversion. The aim of this study was to establish spirometric reference values for Chinese with a national wide sample.
methodsWe enrolled healthy non-smokers in 24 centers in Northeast, North, Northwest, Southwest, South, East and Central China from January 2007 to June 2010. Spirometry was performed according to American Thoracic Society and European Respiratory Society guidelines. Reference equations were established using the Lambda-Mu-Sigma (LMS) method for forced expiratory volume in 1 second (FEV
resultsA total of 7,115 eligible individuals aged 4 to 80 years (50.9% females) were recruited. Reference equations against age and height by gender were established, including predicted values and lower limits of normal (LLNs). Validated with Chinese data, the mean percentage differences of Caucasian reference values adjusted with ethnic conversion factors were -10.2% to 1.8%, and the percentages of total subjects under LLNs were 0.1% to 8.9%. Compared with this study, the percentage differences of previous Chinese studies ranged from -17.8% to 11.4%, which were found to significantly overestimate or underestimate lung function.
conclusionsThis study established new reference values for better interpretation of spirometry in Chinese aged 4 to 80 years, while Caucasian references with adjustment were inappropriate for Chinese.
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