Evidence map›Paper›PMID 29268523›Full record

ArticleJournal of thoracic disease2017

Characteristics of coronary microcirculatory function in patients with Takotsubo syndrome.

Giuseppina Novo, Angelo Quagliana, Dario Buccheri, Salvatore Rizzo, Salvatore Giambanco, Francesco Giambanco, Salvatore Evola, Giovanna Geraci, Salvatore Novo

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuseppina NovoChair and Division of Cardiology, University of Palermo, Palermo, Italy.
Angelo QuaglianaChair and Division of Cardiology, University of Palermo, Palermo, Italy.
Dario BuccheriInterventional Cardiology, San Giovanni di Dio Hospital, Agrigento, Italy.
Salvatore RizzoChair and Division of Cardiology, University of Palermo, Palermo, Italy.
Salvatore GiambancoChair and Division of Cardiology, University of Palermo, Palermo, Italy.
Francesco GiambancoDivision of Cardiology, Ingrassia Hospital, Palermo, Italy.
Salvatore EvolaChair and Division of Cardiology, University of Palermo, Palermo, Italy.
Giovanna GeraciDivision of Cardiology, Cervello Hospital, Palermo, Italy.
Salvatore NovoChair and Division of Cardiology, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTakotsubo syndrome (TS) is a recently described cardiac syndrome whose pathogenesis is still unclear. We investigated the characteristics of coronary microcirculatory function in patients with TS through the analysis of the TIMI frame count (TFC) compared to normal subjects and with to subjects with microvascular angina (MA).

methodsWe enrolled 71 TS patients (F:M =69:2, mean age of 65.27±9.53 years), 70 controls (F:M =34:36, mean age of 56.63±13.5 years) and 71 patients with MA, (F:M =69:2, mean age of 65.9±9.2 years). The assessment of the microcirculation was carried out through the TFC.

resultsmicrocirculation was significantly altered in patients with TS compared with healthy controls [left anterior descending coronary artery (LAD) 25.16±6.91

conclusionsCoronary microcirculation in TS patients is diffuse and milder compared to MA patients. Cut-off values >20 frames discriminate between patients with normal microcirculation and patients with TS.

Indexed as

microvascular angina (MA)microvascular functionTakotsuboTIMI frame count (TFC)

Identifiers

PMID29268523
PMCPMC5721058

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