Evidence map›Paper›PMID 29268521›Full record

ArticleJournal of thoracic disease2017

Stereotactic body radiotherapy (SBRT) for pulmonary metastases from renal cell carcinoma-a multicenter analysis of the German working group "Stereotactic Radiotherapy".

Juliane Hoerner-Rieber, Marciana Duma, Oliver Blanck, Guido Hildebrandt, Andrea Wittig, Fabian Lohaus, Michael Flentje, Frederick Mantel, Robert Krempien, Michael J Eble and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  5. [SBRT for primary renal cell carcinoma-long-term results from the IROCK database].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
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  7. [Stereotactic body radiotherapy as "first-line treatment" for oligometastatic renal cell cancer].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022
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  10. Review
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  15. [Relevance of stereotactic ablative radiotherapy in patients with systemic metastasis].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 2 countries.

Juliane Hoerner-RieberDepartment of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany.
Marciana DumaDepartment of Radiation Oncology, Technical University Munich, Germany.
Oliver BlanckDepartment of Radiation Oncology, UKSH Universitätsklinikum Schleswig-Holstein, Kiel, Germany.
Guido HildebrandtDepartment of Radiation Oncology, University of Rostock, Rostock, Germany.
Andrea WittigDepartment of Radiotherapy and Radiation Oncology, Philipps-University Marburg, University Hospital Giessen and Marburg, Germany.
Fabian LohausDepartment of Radiation Oncology, Medical Faculty and University Hospital C.G. Carus, Technical University Dresden, Germany.
Michael FlentjeDepartment of Radiation Oncology, University Hospital Wuerzburg, Germany.
Frederick MantelDepartment of Radiation Oncology, University Hospital Wuerzburg, Germany.
Robert KrempienDepartment of Radiation Oncology, Helios Klinikum Berlin Buch, Berlin, Germany.
Michael J EbleDepartment of Radiation Oncology, University Hospital Aachen, Aachen, Germany.
Klaus Henning KahlDepartment of Radiation Oncology, Hospital Augsburg, Germany.
Judit Boda-HeggemannDepartment of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Germany.
Stefan RiekenDepartment of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany.
Matthias GuckenbergerDepartment of Radiation Oncology, University Hospital Zurich, University of Zurich, Switzerland.
Heidelberg University · DEUniversity Hospital Schleswig-Holstein · DEHelios Hospital Berlin-Buch · DETechnical University of Munich · DEUniversitätsklinikum Aachen · DEUniversitätsklinikum Gießen und Marburg · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Augsburg · DEUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Heidelberg · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal cell carcinoma (RCC) is traditionally considered to be radioresistant. Radiotherapy response rates are believed to improve with hypofractionated, high dose stereotactic body radiotherapy (SBRT). However, limited data exist regarding the role of SBRT in the treatment of pulmonary metastases.

methodsThe working group "Stereotactic Radiotherapy" of the German Society of Radiation Oncology analyzed its multi-institutional database of more than 700 patients who received SBRT for pulmonary metastases. Treatment was performed at 10 centers between 2001 and 2016. Patients with metastatic RCC were included in the study. Tumor characteristics, treatment details, and follow-up data including survival, local control (LC), distant metastases, and toxicity were evaluated.

resultsA total of 46 RCC patients treated with SBRT for 67 lung metastases were identified, who received a median total biologically effective dose (BED

conclusionsSBRT for pulmonary metastases from RCC was associated with low treatment-associated toxicity, promising survival, and excellent LC, especially in those patients receiving a BED

Indexed as

extracranial stereotactic radiotherapylung metastasesradioresistanceRenal cell carcinoma (RCC)stereotactic body radiotherapy (SBRT)

Identifiers

PMID29268521
PMCPMC5721071
OpenAlexW2767834348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.