ArticleJournal of thoracic disease2017
Rhinovirus is associated with severe adult community-acquired pneumonia in China.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A territory-wide study on adults hospitalized for rhinovirus infection - mortality, severe adverse respiratory and renal outcomes and relationships with multiple comorbidities.Journal of medical microbiology · 2026Article
- Seasonal dynamics and genetic diversity of human rhinoviruses in patients with acute respiratory infection in Bangkok in 2024.Archives of virology · 2025Article
- Post-Engraftment Syndrome Following Autologous Haematopoietic Stem Cell Transplantation in a Patient With Relapsed Hodgkin Lymphoma.Respirology case reports · 2025Article
- Viral non-SARS-CoV-2 etiology of community-acquired pneumonia (CAP) in Southeast Asia: a review and pooled analysis.IJID regions · 2025Review
- Combined NGS and lung biopsy for refractory respiratory failure: a case of HRV and secondary bacterial pneumonia mimicking organizing pneumonia.BMC infectious diseases · 2025Article
- A comparative study of general and severe mycoplasma pneumoniae pneumonia in children.BMC infectious diseases · 2024Article
- Impact of the COVID-19 pandemic on severe non-SARS-CoV-2 community-acquired pneumonia in Reunion Island: a multicenter retrospective observational study, 2016-2021.Scientific reports · 2023Observational
- Clinical significance of Mycoplasma pneumoniae specific IgM titer in children hospitalized with Mycoplasma pneumoniae pneumonia.BMC infectious diseases · 2022Article
- Characteristics, Management, and Outcomes of Community-Acquired Pneumonia Due to Human Rhinovirus-A Retrospective Study.Canadian respiratory journal · 2022Article
- Two Cases of Primary Rhinovirus Pneumonia with Multiple Pulmonary Nodules.Internal medicine (Tokyo, Japan) · 2021Article
- Article
- Clinical, Bronchoscopic, and Imaging Findings of e-Cigarette, or Vaping, Product Use-Associated Lung Injury Among Patients Treated at an Academic Medical Center.JAMA network open · 2020Article
- Molecular Epidemiology of Human Rhinovirus From 1-Year Surveillance Within a School Setting in Rural Coastal Kenya.Open forum infectious diseases · 2020Article
- Primary rhinovirus pneumonia in which bronchoalveolar lavage fluid yielded human rhinovirus.Respiratory medicine case reports · 2019Article
- Influenza and Viral Pneumonia.Clinics in chest medicine · 2018Review
- Erratum to rhinovirus is associated with severe adult community-acquired pneumonia in China.Journal of thoracic disease · 2018Article
- Review
- Distribution of the atypical pathogens of community-acquired pneumonia to disease severity.Journal of thoracic disease · 2018Article
- Rhinovirus Pneumonia, Rhabdomyolysis-Induced Acute Kidney Injury, and Post-Viral Forme Fruste Lupus.Indian journal of nephrologyArticle
Corrections and comments
- Erratum issued
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman rhinovirus (HRV) is one of the most common viral etiologies detected in community-acquired pneumonia (CAP) adult cases. However, few is known about the characteristics of HRV-associated CAP. To describe the clinical features of HRV-associated CAP in immunocompetent adults admitted to multiple medical centers in mainland China over a 2-year period.
methodsA total of 383 patients admitted to hospitals for CAP were enrolled from 46 medical centers in mainland China between January 2013 and December 2014. Multiplex real-time polymerase chain reaction (RT-PCR) assays for viral detection and DNA-based quantitative loop-mediated isothermal amplification (qLAMP) assays for bacterial detection were implemented to all lower respiratory tract specimens obtained from the patients. Twenty-eight cases (28/383, 7.3%) revealed HRV-positive PCR results. Patients with bronchoalveolar lavage (BAL) HRV-positive PCR results (n=20) were further enrolled and divided into two groups depending on the status of bacterial co-infection (viral group, n=12; viral-Bacterial group, n=8). Demographic, clinical and microbiological data were reviewed and compared in detail.
resultsCases with HRV-infection were remarkably correlated with respiratory failure (14/20) and most of them (13/14) received mechanical ventilation. Fever (17/20), productive cough (15/20) and dyspnea (6/20) were common symptoms while flu-like symptoms were rarely observed in the cohort.
conclusionsHRV is a common etiology in CAP among China adults, especially in severe CAP. Clinicians should be vigilant considering of the poor outcome. Highly qualified multiplex PCR techniques with invasive sampling are needed to increase the detection rate.
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