Evidence map›Paper›PMID 29268513›Full record

ArticleJournal of thoracic disease2017

The impact of extreme obesity on outcomes after left ventricular assist device implantation.

Gardner Yost, Laura Coyle, Colleen Gallagher, Nicole Graney, Roxanne Siemeck, Antone Tatooles, Patroklos Pappas, Geetha Bhat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Patient factors associated with left ventricular assist device infections: A scoping review.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022
    Article
  9. Impact of Obesity on Heart Transplantation Outcomes.Journal of the American Heart Association · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gardner YostAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Laura CoyleAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Colleen GallagherAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Nicole GraneyAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Roxanne SiemeckAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Antone TatoolesAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Patroklos PappasAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.
Geetha BhatAdvocate Christ Medical Center, Heart Institute, Heart and Vascular Institute Administration, Oak Lawn, IL 60453, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between extreme body mass index (BMI) and outcomes in left ventricular assist device (LVAD) patients has not been well established. With the commercial use of LVADs a larger number of patients with a BMI >40 have undergone device implantation. The purpose of this study was to evaluate the short and long-term outcomes of LVAD patients with extreme obesity.

methodsA retrospective review of all patients (n=383) at our center who received a LVAD as primary implant between 2005-2015 was performed. Demographics, preoperative laboratory values, and postoperative outcomes were analyzed. Patients were divided into three groups based on BMI (kg/m

resultsComparison of postoperative outcomes demonstrated an increased risk of respiratory failure and right ventricular (RV) failure in patients with a BMI ≥35 (range, 35-59). Length of stay, sternal infection, driveline/pocket infection, systemic infection, GI-bleeding, and neurological events within the first year of device therapy were not related to BMI. Survival at 30-day, 1- and 2-year was not significantly different among the three groups. The group with the smallest BMI demonstrated an increased risk for re-operative bleeding.

conclusionsDespite an increased risk of early morbidity in patients with extreme obesity, long term survival was not significantly different between the BMI groups. Careful consideration is recommended when evaluating patients with an excessive BMI for LVAD therapy although it should not be a contraindication for device placement.

Indexed as

left ventricular assist device (LVAD)Obesityoutcomes

Identifiers

PMID29268513
PMCPMC5721063

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.