Evidence map›Paper›PMID 29268385›Full record

ArticleJournal of thoracic disease2017

Macrolide-resistant

Yu-Dong Yin, Rui Wang, Chao Zhuo, Hui Wang, Ming-Gui Wang, Can-Mao Xie, Dan-Yang She, Xin Yuan, Ren-Tao Wang, Bin Cao and 1 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04126304 (Multi-center Investigation and Study of Mycoplasma Pneumoniae Infection and Macrolide Drug Resistance in Outpatient and In-hospital Pediatric Acute Respiratory Diseases Illness in China), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04126304 unknown statusnot on this mapstarted 2019, after this paper: background citation

Multi-center Investigation and Study of Mycoplasma Pneumoniae Infection and Macrolide Drug Resistance in Outpatient and In-hospital Pediatric Acute Respiratory Diseases Illness in China

TypeobservationalSponsorShanghai Children's Medical CenterRan2019 to 2021Enrolled2,312ConditionsRespiratory Tract InfectionsArmsAzithromycin, non-macrolides antibiotics, Mycoplasma detection, Data collection
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Macrolide-resistantFrontiers in pediatrics · 2026
    Article
  5. Frontiers in microbiology · 2026
    Article
  6. Antimicrobial activity of lefamulin against pathogens most commonly causing community-acquired pneumonia: results from the China antimicrobial surveillance network in 2020-2022.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Macrolide resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  11. Article
  12. A comprehensive review ofFrontiers in medicine · 2024
    Review
  13. Case Report: Omadacycline in the treatment of macrolide-unresponsiveFrontiers in cellular and infection microbiology · 2023
    Article
  14. Article
  15. Article
  16. Molecular Detection and Evaluation of MLـ ResistanceReports of biochemistry & molecular biology · 2020
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Yu-Dong YinDepartment of Infectious Diseases and Clinical Microbiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Rui WangDepartment of Clinical Pharmacology, PLA General Hospital, Beijing 100853, China.
Chao ZhuoState Key Laboratory of Respiratory Diseases, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510000, China.
Hui WangDepartment of Laboratory Medicine, Peking University People's Hospital, Beijing 100044, China.
Ming-Gui WangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, China.
Can-Mao XieDepartment of Respiratory Medicine, the First Affiliated Hospital of Sun Yat-sen University, Institute of Respiratory Diseases of Sun Yat-sen University, Guangzhou 510080, China.
Dan-Yang SheDepartment of Respiratory Diseases, PLA General Hospital, Beijing 100853, China.
Xin YuanDepartment of Respiratory and Critical Care Medicine, the Affiliated Hospital of the Academy of Military Medical Science, Beijing 100071, China.
Ren-Tao WangDepartment of Respiratory Diseases, PLA General Hospital, Beijing 100853, China.
Bin CaoDepartment of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
You-Ning LiuDepartment of Respiratory Diseases, PLA General Hospital, Beijing 100853, China.
Chinese PLA General Hospital · CNAcademy of Military Medical Sciences · CNBeijing Chao-Yang Hospital · CNChina-Japan Friendship Hospital · CNGuangzhou Medical University · CNHuashan Hospital · CNPeking University People's Hospital · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug resistant

methodsThis is a prospectively designed multicenter study conducted on adult patients with CAP visiting six teaching hospitals in the cities of Beijing, Shanghai and Guangzhou between September 2010 and June 2012.

resultsA total of 520 adult patients (mean age: 45.7±26.2 years) with CAP visiting teaching hospitals in the cities of Beijing, Shanghai and Guangzhou were included. Of the 520 patients, only 75 (14.42%) were confirmed

conclusionsHigh resistance was observed with macrolides, whereas, none of the MP strains were resistant to fluoroquinolones and TET. Hence, macrolide resistant MP (MRMP)_infections could be well treated with fluoroquinolones. However, few isolated strains had minimal inhibitory concentration (MIC) values on the edge of resistance to quinolones, alarming a quinolone-resistant

Indexed as

antibiotic resistancebeta-lactamsfluoroquinolonesMycoplasma pneumoniae (MP)point mutation

Identifiers

PMID29268385
PMCPMC5723809
OpenAlexW2762679961

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.