Evidence map›Paper›PMID 29267448›Full record

ArticleAnais brasileiros de dermatologia2017

Deferasirox-induced urticarial vasculitis in a patient with myelodysplastic syndrome.

Asude Kara Polat, Asli Akin Belli, Volkan Karakus, Yelda Dere

Open access · goldAbstract readCase Reports
In one paragraph

Article in Anais brasileiros de dermatologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Asude Kara PolatDepartment of Dermatology, Istanbul Training and Research Hospital - Istanbul, Turkey.
Asli Akin BelliDepartment of Dermatology, Mugla Sitki Kocman University Training and Research Hospital - Mugla, Turkey.
Volkan KarakusDepartment of Hematology, Mugla Sitki Kocman University Training and Research Hospital - Mugla, Turkey.
Yelda DereDepartment of Pathology, Mugla Sitki Kocman University, Faculty of Medicine - Mugla, Turkey.
Muğla University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deferasirox is an iron chelator agent used in the treatment of diseases with iron overload, such as thalassemia and myelodysplastic syndrome. Although the majority of adverse reactions of deferasirox involve gastrointestinal symptoms and increase in serum creatinine and transaminases, skin rashes, such as maculopapular and urticarial eruptions, have also been reported. This study reports a case of myelodysplastic syndrome with urticarial vasculitis due to deferasirox therapy. Drug eruption was been confirmed by means of a challenge test, together with histopathological and clinical findings. To the best of our knowledge, we report the first case of deferasirox-induced urticarial vasculitis. Physicians should be aware of the possibility of urticarial vasculitis on deferasirox therapy and the fact that the discontinuation of the drug generally results in improvement.

Indexed as

AgedBenzoatesBiopsyDeferasiroxDrug EruptionsFemaleHumansIron Chelating AgentsMyelodysplastic SyndromesTriazolesUrticariaVasculitisBenzoatesDeferasiroxIron Chelating AgentsTriazoles

Identifiers

PMID29267448
PMCPMC5726679
OpenAlexW2775369473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.