SynthesisPloS one2017
Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis.
Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 20 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
136 citing papers in PubMed, 20 syntheses or guidelines pooled it, 279 citations in OpenAlex.
- Efficacy and Acceptability of Digital and Web-Based Interventions for Stress and Burnout Among Physicians: A Systematic Review and Meta-analysis.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026Pooled it
- Optimizing Workplace Digital Mental Health Interventions: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Could the use of web-based applications assist in neuropsychiatric treatment? An umbrella review.BMC psychology · 2025Pooled it
- Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation.BMJ open · 2025Pooled it
- Effectiveness of Digital Mental Health Interventions in the Workplace: Umbrella Review of Systematic Reviews.JMIR mental health · 2025Pooled it
- What internet- and mobile-based interventions are currently available for adults with overweight or obesity experiencing symptoms of depression? A systematic review.International journal of obesity (2005) · 2025Pooled it
- Differential attrition and engagement in randomized controlled trials of occupational mental health interventions in person and online: A systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2024Pooled it
- Effects of interventions implemented by occupational health professionals to prevent work-related stress complaints: a systematic review.Occupational and environmental medicine · 2024Pooled it
- The effectiveness of e-mental health interventions on stress, anxiety, and depression among healthcare professionals: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Universal, selective and indicated interventions for supporting mental health at the workplace: an umbrella review of meta-analyses.Occupational and environmental medicine · 2023Pooled it
- Providing Human Support for the Use of Digital Mental Health Interventions: Systematic Meta-review.Journal of medical Internet research · 2023Pooled it
- The Effectiveness of eHealth Interventions on Lifestyle Modification in Patients With Nonalcoholic Fatty Liver Disease: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Trends in Effectiveness of Organizational eHealth Interventions in Addressing Employee Mental Health: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022Pooled it
- Effectiveness of telemonitoring on self-care behaviors among community-dwelling adults with heart failure: a quantitative systematic review.JBI evidence synthesis · 2021Pooled it
- eHealth in the support of people with mild intellectual disability in daily life: A systematic review.Journal of applied research in intellectual disabilities : JARID · 2020Pooled it
- Mobile Apps for Mental Health Issues: Meta-Review of Meta-Analyses.JMIR mHealth and uHealth · 2020Pooled it
- A Systematic Review of the Evidence Supporting Mobile- and Internet-Based Psychological Interventions For Self-Harm.Suicide & life-threatening behavior · 2020Pooled it
- Telemedicine in the OECD: An umbrella review of clinical and cost-effectiveness, patient experience and implementation.PloS one · 2020Pooled it
- Rapid Review and Meta-Meta-Analysis of Self-Guided Interventions to Address Anxiety, Depression, and Stress During COVID-19 Social Distancing.Frontiers in psychology · 2020Pooled it
76 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany organisations promote eHealth applications as a feasible, low-cost method of addressing mental ill-health and stress amongst their employees. However, there are good reasons why the efficacy identified in clinical or other samples may not generalize to employees, and many Apps are being developed specifically for this group. The aim of this paper is to conduct the first comprehensive systematic review and meta-analysis evaluating the evidence for the effectiveness and examine the relative efficacy of different types of eHealth interventions for employees.
methodsSystematic searches were conducted for relevant articles published from 1975 until November 17, 2016, of trials of eHealth mental health interventions (App or web-based) focused on the mental health of employees. The quality and bias of all identified studies was assessed. We extracted means and standard deviations from published reports, comparing the difference in effect sizes (Hedge's g) in standardized mental health outcomes. We meta-analysed these using a random effects model, stratified by length of follow up, intervention type, and whether the intervention was universal (unselected) or targeted to selected groups e.g. "stressed".
results23 controlled trials of eHealth interventions were identified which overall suggested a small positive effect at both post intervention (g = 0.24, 95% CI 0.13 to 0.35) and follow up (g = 0.23, 95% CI 0.03 to 0.42). There were differential short term effects seen between the intervention types whereby Mindfulness based interventions (g = 0.60, 95% CI 0.34 to 0.85, n = 6) showed larger effects than the Cognitive Behaviour Therapy (CBT) based (g = 0.15, 95% CI 0.02 to 0.29, n = 11) and Stress Management based (g = 0.17, 95%CI -0.01 to 0.34, n = 6) interventions. The Stress Management interventions however differed by whether delivered to universal or targeted groups with a moderately large effect size at both post-intervention (g = 0.64, 95% CI 0.54 to 0.85) and follow-up (g = 0.69, 95% CI 0.06 to 1.33) in targeted groups, but no effect in unselected groups.
interpretationThere is reasonable evidence that eHealth interventions delivered to employees may reduce mental health and stress symptoms post intervention and still have a benefit, although reduced at follow-up. Despite the enthusiasm in the corporate world for such approaches, employers and other organisations should be aware not all such interventions are equal, many lack evidence, and achieving the best outcomes depends upon providing the right type of intervention to the correct population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.