ArticlePloS one
Utility of quick sepsis-related organ failure assessment (qSOFA) to predict outcome in patients with pneumonia.
Article in PloS one. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of qSOFA in predicting mortality of pneumonia: A systematic review and meta-analysis.Medicine · 2018Pooled it
- Quick sequential organ failure assessment versus systemic inflammatory response syndrome criteria for emergency department patients with suspected infection.Scientific reports · 2021Trial
- Comparison of CURB-65 and qSOFA scores in predicting outcomes in community-acquired pneumonia.Annals of medicine and surgery (2012) · 2026Article
- Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study.Annals of medicine · 2025Article
- Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study.EClinicalMedicine · 2025Article
- Comparative Effectiveness of CURB-65 and qSOFA Scores in Predicting Pneumonia Outcomes: A Systematic Review.Cureus · 2024Review
- Utility of quick sepsis-related organ failure assessment (qSOFA) score to predict outcomes in out-of-ICU patients with suspected infections.Journal of family medicine and primary care · 2020Article
- Prognostic accuracy of SIRS criteria and qSOFA score for in-hospital mortality among influenza patients in the emergency department.BMC infectious diseases · 2020Article
- The quick Sepsis-related Organ Failure Assessment (qSOFA) is a good predictor of in-hospital mortality in very elderly patients with bloodstream infections: A retrospective observational study.Scientific reports · 2019Observational
- Application of The Sepsis-3 Consensus Criteria in a Geriatric Acute Care Unit: A Prospective Study.Journal of clinical medicine · 2019Article
- qSOFA is a Poor Predictor of Short-Term Mortality in All Patients: A Systematic Review of 410,000 Patients.Journal of clinical medicine · 2019Review
- Early identification of severe community-acquired pneumonia: a retrospective observational study.BMJ open respiratory research · 2019Observational
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite on-going advances in medical treatment, the burden of disease of pneumonia remains high. We aimed to determine the association of the qSOFA score with in-hospital mortality, length of hospitalisation, and admission to the intensive care unit (ICU) in patients with pneumonia. Further, in a subgroup analysis, the outcomes were compared for qSOFA in comparison to other risk scores, including the CURB-65 and SIRS scores.
methodsIn a retrospective analysis, admission data from the ED of the Bern University Hospital, Switzerland, were screened to identify patients admitted for pneumonia. In addition to clinical characteristics, qSOFA and CURB-65 scores and SIRS criteria were assessed and evaluated with respect to the defined study outcomes.
results527 patients (median age 66 IQR 50-76) were included in this study. The overall in-hospital mortality was 13.3% (n = 70); 22.0% (n = 116) were transferred to the ICU. The median length of hospitalisation was 7 days (IQR 4-12). In comparison to qSOFA-negative patients, qSOFA-positive patients had increased odds ratios for in-hospital mortality (OR 2.6, 95%:1.4, 4.7, p<0.001) and ICU admission (3.5, 95% CI: 2.0. 5.8, p<0.001) and an increased length of stay (p<0.001). For ICU admission, the specificity of qSOPA-positivity (≥2) was 82.1% and sensitivity 43.0%. For in-hospital mortality, the specificity of qSOPA-positivity (≤2) was 88.9% and sensitivity 24.4%. In the subgroup analysis (n = 366). The area under the receiver operating curve for ICU admission was higher for qSOFA than for the CURB-65 score (p = 0.013). The evaluated scores did not differ significantly in their prognostication of in-hospital mortality (p>0.05).
conclusionsThe qSOFA score is associated with in-hospital mortality, ICU admission and length of hospitalisation in ED patients with pneumonia. Subgroup analysis revealed that qSOFA is superior to CURB-65 in respect to prognostication of ICU admission.
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