ReviewToxics2017
Persistent Threats by Persistent Pollutants: Chemical Nature, Concerns and Future Policy Regarding PCBs-What Are We Heading For?
Review in Toxics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Association between polychlorinated biphenyls and hypertension risk: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Advancing the Discovery of Emerging Contaminants: A Leap in Technology and Data.Environmental science & technology · 2026Review
- Polychlorinated Biphenyls, Oxidative Stress, and Brain Health: Mechanistic Links to Neurodegenerative and Neurodevelopmental Diseases.Antioxidants (Basel, Switzerland) · 2026Review
- Effects of polychlorinated biphenyls on the peripheral and central auditory systems.Hearing research · 2025Review
- Early-life exposure to PCBs and PFAS exerts negative effects on the developing central nervous system.Journal of hazardous materials · 2025Review
- Review
- QSTR Models in Dioxins and Dioxin-like Compounds Provide Insights into Gene Expression Dysregulation.Toxics · 2024Article
- Developmental exposure to the Fox River PCB mixture modulates behavior in juvenile mice.Neurotoxicology · 2024Article
- Earth at risk: An urgent call to end the age of destruction and forge a just and sustainable future.PNAS nexus · 2024Review
- High-Throughput GPCRome Screen of Pollutants Reveals the Activity of Polychlorinated Biphenyls at Melatonin and Sphingosine-1-phosphate Receptors.Chemical research in toxicology · 2024Article
- Assessing Metabolic Differences Associated with Exposure to Polybrominated Biphenyl and Polychlorinated Biphenyls in the Michigan PBB Registry.Environmental health perspectives · 2023Article
- Pubertal progression in relation to peripubertal exposure to organochlorine chemicals in a cohort of Russian boys.International journal of hygiene and environmental health · 2023Article
- Induction of Oxidative Stress and Alteration of Synaptic Gene Expression in Newborn Hippocampal Granule Cells after Developmental Exposure to Aroclor 1254.Neuroendocrinology · 2023Article
- A semi-analytical solution to organic contaminants transport through composite liners considering a single crack in CCL.Environmental science and pollution research international · 2022Article
- Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure.Cell reports · 2022Article
- Augmentation of an Engineered Bacterial Strain Potentially Improves the Cleanup of PCB Water Pollution.Microbiology spectrum · 2021Article
- 'Cry-for-help' in contaminated soil: a dialogue among plants and soil microbiome to survive in hostile conditions.Environmental microbiology · 2021Review
- Sex-specific Associations Between Type 2 Diabetes Incidence and Exposure to Dioxin and Dioxin-like Pollutants: A Meta-analysis.Frontiers in toxicology · 2021Review
- Halogen Bonding Interactions of Polychlorinated Biphenyls and the Potential for Thyroid Disruption.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- A Halogen Bonding Perspective on Iodothyronine Deiodinase Activity.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polychlorinated biphenyl (PCB)-contaminated sites around the world affect human health for many years, showing long latency periods of health effects. The impact of the different PCB congeners on human health should not be underestimated, as they are ubiquitous, stable molecules and reactive in biological tissues, leading to neurological, endocrine, genetic, and systemic adverse effects in the human body. Moreover, bioaccumulation of these compounds in fatty tissues of animals (e.g., fish and mammals) and in soils/sediments, results in chronic exposure to these substances. Efficient destruction methods are important to decontaminate polluted sites worldwide. This paper provides an in-depth overview of (i) the history and accidents with PCBs in the 20th century, (ii) the mechanisms that are responsible for the hazardous effects of PCBs, and (iii) the current policy regarding PCB control and decontamination. Contemporary impacts on human health of historical incidents are discussed next to an up to date overview of the health effects caused by PCBs and their mechanisms. Methods to decontaminate sites are reviewed. Steps which lead to a policy of banning the production and distribution of PCBs are overviewed in a context of preventing future accidents and harm to the environment and human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.