Evidence map›Paper›PMID 29267198›Full record

ReviewInternational journal of environmental research and public health2017

Water Quality and Brain Function.

Stephen C Bondy, Arezoo Campbell

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Review
  7. Foreign Contaminants Target Brain Health.CNS & neurological disorders drug targets · 2025
    Review
  8. Water pollution and the brain.Clinics (Sao Paulo, Brazil) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Examining Community Engagement Research Strategies Used in Flint, Michigan: The Church Challenge.Progress in community health partnerships : research, education, and action · 2023
    Article
  14. Article
  15. Article
  16. Nature-based coagulants for drinking water treatment: An ecotoxicological overview.Water environment research : a research publication of the Water Environment Federation · 2022
    Article
  17. Article
  18. Article
  19. Structured water: effects on animals.Journal of animal science · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Stephen C BondyCenter for Occupational and Environmental Health, Department of Medicine, University of California, Irvine, CA 92617-1830, USA. scbondy@uci.edu.ORCID 0000-0001-5158-2993
Arezoo CampbellDepartment of Pharmaceutical Sciences, Western University of Health Sciences, Pomona, CA 91766-1854, USA. acampbell@westernu.edu.
University of California, Irvine · USWestern University of Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the United States, regulations are in place to ensure the quality of drinking water. Such precautions are intended to safeguard the health of the population. However, regulatory guidelines may at times fail to achieve their purpose. This may be due to lack of sufficient data regarding the health hazards of chronic low dose exposure to contaminants or the introduction of new substances that pose a health hazard risk that has yet to be identified. In this review, examples of different sources of contaminants in drinking water will be discussed, followed by an evaluation of some select individual toxicants with known adverse neurological impact. The ability of mixtures to potentially cause additive, synergistic, or antagonistic neurotoxic responses will be briefly addressed. The last section of the review will provide examples of select mechanisms by which different classes of contaminants may lead to neurological impairments. The main objective of this review is to bring to light the importance of considering trace amounts of chemicals in the drinking water and potential brain abnormalities. There is continued need for toxicology studies to better understand negative consequences of trace amounts of toxins and although it is beyond the scope of this brief overview it is hoped that the review will underscore the paucity of studies focused on determining how long-term exposure to minute levels of contaminants in drinking water may pose a significant health hazard.

Indexed as

BrainHazardous SubstancesHumansNeurotoxinsUnited StatesWater Pollutants, ChemicalWater QualityWater SupplyHazardous SubstancesNeurotoxinsWater Pollutants, Chemicalbrain functiondrinking water qualityneurotoxic metalsneurotoxic organicspublic healthreservoirs

Identifiers

PMID29267198
PMCPMC5800103
OpenAlexW2781318371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.