Evidence map›Paper›PMID 29266709›Full record

ArticleJournal of cellular and molecular medicine2018

Gallic acid attenuates calcium calmodulin-dependent kinase II-induced apoptosis in spontaneously hypertensive rats.

Li Jin, Zhe Hao Piao, Chun Ping Liu, Simei Sun, Bin Liu, Gwi Ran Kim, Sin Young Choi, Yuhee Ryu, Hae Jin Kee, Myung Ho Jeong

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Role of gallic acid in sarcopenia in D-galactose-treated mice.Iranian journal of basic medical sciences · 2026
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  8. Angiotensin-(1-9) prevents angiotensin II-induced endothelial apoptosis through CNPY2/PERK pathway.Apoptosis : an international journal on programmed cell death · 2023
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  12. Probing Changes in CaMicromachines · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Li JinHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Zhe Hao PiaoThe Second Hospital of Jilin University, Nanguan, Changchun, China.
Chun Ping LiuJilin Hospital Affiliated with Jilin University, Chuanying, Jilin, China.
Simei SunHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Bin LiuThe Second Hospital of Jilin University, Nanguan, Changchun, China.
Gwi Ran KimHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Sin Young ChoiHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Yuhee RyuHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Hae Jin KeeHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.ORCID 0000-0002-9774-4828
Myung Ho JeongHeart Research Center of Chonnam National University Hospital, Gwangju, Korea.
Chonnam National University Hospital · KRJilin University · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension causes cardiac hypertrophy and leads to heart failure. Apoptotic cells are common in hypertensive hearts. Ca

Indexed as

Angiotensin IIAnimalsAntihypertensive AgentsApoptosisAtrial Natriuretic Factorbcl-2-Associated X ProteinBlood PressureCalcium-Calmodulin-Dependent Protein Kinase Type 2Cardiotonic AgentsCaspase 3Cell LineGallic AcidGene Expression RegulationHypertensionHypertrophy, Left VentricularIsoenzymesAngiotensin IIAntihypertensive AgentsAtrial Natriuretic FactorBax protein, ratbcl-2-Associated X ProteinCalcium-Calmodulin-Dependent Protein Kinase Type 2Cardiotonic AgentsCasp3 protein, ratCaspase 3Gallic AcidIsoenzymesNatriuretic Peptide, BrainNitric Oxide Synthasep300-CBP-Associated Factorp300-CBP Transcription FactorsTumor Suppressor Protein p53apoptosisCa2+/calmodulin-dependent protein kinase IIcardiac hypertrophygallic acidspontaneously hypertensive rats (SHR)

Identifiers

PMID29266709
PMCPMC5824377
OpenAlexW2781258425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.