ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2018
Unshielded magnetocardiography: Repeatability and reproducibility of automatically estimated ventricular repolarization parameters in 204 healthy subjects.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 18 citations in OpenAlex.
- Non-Invasive Mapping of Ventricular Action Potential Reconstructed from Contactless Magnetocardiographic Recordings in Intact and Conscious Guinea Pigs.Journal of cardiovascular development and disease · 2025Article
- Non-invasive mapping of ventricular action potential waveforms reconstructed from clinical unshielded magnetocardiography. Potential diagnostic application and current limitations.American heart journal plus : cardiology research and practice · 2025Article
- Advances of magnetocardiography in application of adult and fetal cardiac diseases.Frontiers in cardiovascular medicine · 2025Review
- New clinical application of magnetocardiography: diagnosis of left ventricular hypertrophy.Frontiers in cardiovascular medicine · 2025Article
- Evaluation of coronary microvascular dysfunction using magnetocardiography: A new application to an old technology.American heart journal plus : cardiology research and practice · 2024Article
- Clinical magnetocardiography: the unshielded bet-past, present, and future.Frontiers in cardiovascular medicine · 2023Review
- [Key technologies for intelligent brain-computer interaction based on magnetoencephalography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022Article
- Review
- Effectiveness of magnetocardiography to identify patients in need of coronary artery revascularization: a cross-sectional study.Cardiovascular diagnosis and therapy · 2020Article
- Noninvasive muscle activity imaging using magnetography.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Toward a novel semi-invasive activation mapping tool for the diagnosis of supraventricular arrhythmias from the esophagus.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019Observational
- Unshielded magnetocardiography: Repeatability and reproducibility of automatically estimated ventricular repolarization parameters in 204 healthy subjects.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetocardiographic mapping (MCG) provides quantitative assessment of the magnetic field (MF) induced by cardiac ionic currents, is more sensitive to tangential currents, and measures vortex currents undetectable by ECG, with higher reported sensitivity of MCG ventricular repolarization (VR) parameters for earlier detection of acute myocardial ischemia. Aims of this study were to validate the feasibility of in-hospital unshielded MCG and to assess repeatability and reproducibility of quantitative VR parameters, considering also possible gender- and age-related variability.
methodsMCG of 204 healthy subjects [114 males-mean age 43.4 ± 17.3 and 90 females-mean age 40.2 ± 15.7] was retrospectively analyzed, with a patented proprietary software automatically estimating twelve VR parameters derived from the analysis of the dynamics of the T-wave MF extrema (five parameters) and from the inverse solution with the effective magnetic dipole model giving the effective magnetic vector components (seven parameters). MCG repeatability was calculated as coefficient of variation (CV) ±standard error of the mean (SEM). Reproducibility was assessed as intraclass correlation coefficient (ICC).
resultsThe repeatability of all MCG parameters was 16 ± 1.2 (%) (average CV ± SEM). Optimal (ICC > 0.7) reproducibility was found for 11/12 parameters (mean values) and in 8/12 parameters (single values). No significant gender-related difference was observed; six parameters showed a strong/moderate correlation with age.
conclusionReliable MCG can be performed into an unshielded hospital ambulatory, with repeatability and reproducibility of quantitative assessment of VR adequate for clinical purposes. Wider clinical use is foreseen with the development of multichannel optical magnetometry.
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