Evidence map›Paper›PMID 29266472›Full record

ReviewInternational journal of urology : official journal of the Japanese Urological Association2018

Current treatment strategies for advanced prostate cancer.

Kazumasa Komura, Christopher J Sweeney, Teruo Inamoto, Naokazu Ibuki, Haruhito Azuma, Philip W Kantoff

Abstract readReview
In one paragraph

Review in International journal of urology : official journal of the Japanese Urological Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Gleason pattern 5 is associated with an increased risk for metastasis following androgen deprivation therapy and radiation: An analysis of RTOG 9202 and 9902.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2019
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  12. Review
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  14. Current Evidence on Cabazitaxel for Prostate Cancer Therapy: A Narrative Review.International journal of urology : official journal of the Japanese Urological Association · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kazumasa KomuraDepartment of Urology, Osaka Medical College, Takatsuki, Osaka, Japan.
Christopher J SweeneyDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Teruo InamotoDepartment of Urology, Osaka Medical College, Takatsuki, Osaka, Japan.
Naokazu IbukiDepartment of Urology, Osaka Medical College, Takatsuki, Osaka, Japan.
Haruhito AzumaDepartment of Urology, Osaka Medical College, Takatsuki, Osaka, Japan.
Philip W KantoffDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

During the past decade, treatment strategies for patients with advanced prostate cancer involving stage IV (T4N0M0, N1M0 or M1) hormone-sensitive prostate cancer and recurrent prostate cancer after treatment with curative intent, as well as castration-resistant prostate cancer, have extensively evolved with the introduction and approval of several new agents including sipuleucel-T, radium-223, abiraterone, enzalutamide and cabazitaxel, all of which have shown significant improvement on overall survival. The appropriate use of these agents and the proper sequencing of these agents are still not optimized. The results of several recently reported randomized controlled trials and retrospective studies could assist in developing a treatment strategy for advanced prostate cancer. In addition, prospective studies and molecular characterization of tumors to address these issues are ongoing.

Indexed as

Neoplasm Recurrence, LocalProstatic NeoplasmsAlgorithmsAntineoplastic AgentsBiomarkers, TumorCancer VaccinesHumansMalePrognosisProstatic Neoplasms, Castration-ResistantRadiumRandomized Controlled Trials as TopicTissue ExtractsAntineoplastic AgentsBiomarkers, TumorCancer VaccinesRadiumRadium-223sipuleucel-TTissue Extractscastration-resistant prostate cancerprecision medicineprostate cancersequential therapy

Identifiers

PMID29266472
PMCPMC6053280

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.