Evidence map›Paper›PMID 29266420›Full record

ArticleHuman psychopharmacology2018

Short circuit: Disaggregation of adrenocorticotropic hormone and cortisol levels in HIV-positive, methamphetamine-using men who have sex with men.

Adam W Carrico, Violeta J Rodriguez, Deborah L Jones, Mahendra Kumar

Open access · greenAbstract read
In one paragraph

Article in Human psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Adam W CarricoDepartment of Public Health Sciences, University of Miami, School of Medicine, Miami, Florida, USA.ORCID 0000-0002-8146-5701
Violeta J RodriguezDepartment of Psychiatry and Behavioral Sciences, University of Miami, School of Medicine, Miami, Florida, USA.ORCID 0000-0001-8543-2061
Deborah L JonesDepartment of Psychiatry and Behavioral Sciences, University of Miami, School of Medicine, Miami, Florida, USA.ORCID 0000-0002-0309-0334
Mahendra KumarDepartment of Psychiatry and Behavioral Sciences, University of Miami, School of Medicine, Miami, Florida, USA.ORCID 0000-0002-3711-0540
University of Miami · US

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
HIV-1 Infection in Methamphetamine Abusers: Endocrine OutcomesR01DA031201 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KUMAR, MAHENDRA · 2011 to 2015
$2.9M
NIAID NIH HHS P30 AI073961NIDA NIH HHS R01 DA031201
6 · The paper itself

Abstract

objectiveThis study examined if methamphetamine use alone (METH + HIV-) and methamphetamine use in combination with HIV (METH + HIV+) were associated with hypothalamic-pituitary-adrenal (HPA) axis dysregulation as well as insulin resistance relative to a nonmethamphetamine-using, HIV-negative comparison group (METH-HIV-).

methodsUsing an intact groups design, serum levels of HPA axis hormones in 46 METH + HIV- and 127 METH + HIV+ men who have sex with men (MSM) were compared to 136 METH-HIV- men.

resultsThere were no group differences in prevailing adrenocorticotropic hormone (ACTH) or cortisol levels, but the association between ACTH and cortisol was moderated by METH + HIV+ group (β = -0.19, p < .05). Compared to METH-HIV- men, METH + HIV+ MSM displayed 10% higher log

conclusionsFurther research is needed to characterize the bio-behavioral pathways that explain dysregulated HPA axis functioning in HIV-positive, methamphetamine-using MSM.

Indexed as

Homosexuality, MaleAdolescentAdrenocorticotropic HormoneAdultAmphetamine-Related DisordersCentral Nervous System StimulantsHIV InfectionsHumansHydrocortisoneInsulin ResistanceMaleMethamphetamineMiddle AgedSexual and Gender MinoritiesYoung AdultAdrenocorticotropic HormoneCentral Nervous System StimulantsHydrocortisoneMethamphetamineadrenocorticotropic hormonecortisolHIVinsulinmethamphetamineSyndemic

Identifiers

PMID29266420
PMCPMC5786481
OpenAlexW2781142830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.