ReviewBritish journal of pharmacology2018
Phages of life - the path to pharma.
Review in British journal of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Complementary killing activities ofAntimicrobial agents and chemotherapy · 2025Article
- Phage and Endolysin Therapy Against Antibiotics Resistant Bacteria: From Bench to Bedside.MedComm · 2025Review
- Reply: Response to Phage Therapy in Korea: A Prescribers' Survey of Attitudes Amongst Korean Infectious Diseases Specialists Towards Phage Therapy.Infection & chemotherapy · 2024Article
- Review
- Effective reduction ofFrontiers in microbiology · 2023Article
- In Vivo Recovery of Bacteriophages and Their Effects onVeterinary sciences · 2022Article
- Fighting Antibiotic Resistance in Hospital-Acquired Infections: Current State and Emerging Technologies in Disease Prevention, Diagnostics and Therapy.Frontiers in microbiology · 2021Review
- Bacteriophages Against Pathogenic Bacteria and Possibilities for Future Application in Africa.Infection and drug resistance · 2021Review
- Development of a Bacteriophage Cocktail to Constrain the Emergence of Phage-ResistantFrontiers in microbiology · 2020Article
- Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Article
- Viruses and immunosenescence - more players in the game.Immunity & ageing : I & A · 2019Review
- When pharmacology meets the microbiome: new targets for therapeutics?British journal of pharmacology · 2018Article
- Article
- Microbiota and Phage Therapy: Future Challenges in Medicine.Medical sciences (Basel, Switzerland) · 2018Review
- Review
- Review
- Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile.Nature communications · 2018Article
- Bacteriophages: Protagonists of a Post-Antibiotic Era.Antibiotics (Basel, Switzerland) · 2018Review
- Phages of life - the path to pharma.British journal of pharmacology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophage (phage) therapy has encountered both enthusiasm and scepticism in the past century. New antimicrobial strategies against lethal pathogens are now a top priority for the World Health Organization, and although compassionate use of phages recently met with significant success, regulated clinical interventions seem unlikely in the near future. The hundredth anniversary of their discovery seems an appropriate time for a revival of phage therapy, particularly as the dilemma of antibiotic resistance grows. Phages are ubiquitous in the environment, on our food and in and on our bodies. Their influence on human health is currently being evaluated, and in this mini-review, we examine data from recent metagenomic studies that propose a role for phages in the structure of the microbiome and in health and disease. We assess evidence for phages as vehicles for gene transfer in the context of antibiotic resistance and discuss challenges and opportunities along the critical path from phage discovery to a patient-focused pharmaceutical intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.