ReviewAnnals of the New York Academy of Sciences2017
Tissue-specific endothelial cells: a promising approach for augmentation of soft tissue repair in orthopedics.
Review in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Review
- Cell lineage tracing and functional assessment of supraspinatus tendon healing in an acute repair murine model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021Article
- SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging.Molecular therapy. Nucleic acids · 2021Article
- Endothelial cell function and endothelial-related disorders following haematopoietic cell transplantation.British journal of haematology · 2020Review
- Cell Therapy-a Basic Science Primer for the Sports Medicine Clinician.Current reviews in musculoskeletal medicine · 2019Review
- Genetic lineage tracing of targeted cell populations during enthesis healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018Article
- Common Injuries and Repair Mechanisms in the Endothelial Lining.Chinese medical journal · 2018Review
- The more critical murderer of atherosclerosis than lipid metabolism: chronic stress.Lipids in health and disease · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Biologics are playing an increasingly significant role in the practice of modern medicine and surgery in general and orthopedics in particular. Cell-based approaches are among the most important and widely used modalities in orthopedic biologics, with mesenchymal stem cells and other multi/pluripotent cells undergoing evaluation in numerous preclinical and clinical studies. On the other hand, fully differentiated endothelial cells (ECs) have been found to perform critical roles in homeostasis of visceral tissues through production of an adaptive panel of so-called "angiocrine factors." This newly discovered function of ECs renders them excellent candidates for novel approaches in cell-based biologics. Here, we present a review of the role of ECs and angiocrine factors in some visceral tissues, followed by an overview of current cell-based approaches and a discussion of the potential applications of ECs in soft tissue repair.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.