ArticleThe Indian journal of medical research2017
Late effects of treatment in survivors of childhood cancers: A single-centre experience.
Article in The Indian journal of medical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Physical late effects of treatment among survivors of childhood cancer in low- and middle-income countries: a systematic review.Journal of cancer survivorship : research and practice · 2025Pooled it
- Hepatic late adverse effects after antineoplastic treatment for childhood cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Long term outcomes of the Indian childhood cancer survivorship (C2S) cohort: a multicentre study (2016-2024).The Lancet regional health. Southeast Asia · 2026Article
- Chemotherapy-Induced Toxicities in Pediatric Cancer Patients: A Cross-Sectional Survey Using a Child- and Caregiver-Reported Outcome Tool in Tanzania.Drug, healthcare and patient safety · 2026Article
- Bridging gaps in oncofertility: evaluation of reproductive dysfunction and fertility assessment in pediatric cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Development of Communication and Language Skills in Children with Hematological-Oncological Disorders: Challenges and Perspectives.Children (Basel, Switzerland) · 2025Article
- Parental Reports on Late Effects and Follow-Up Needs: A Single-Center Assessment of Childhood Cancer Survivorship Care in Kenya.Current oncology (Toronto, Ont.) · 2025Article
- Childhood Cancer Survivorship Care in Limited Resource Settings: A Narrative Review and Strategies to Promote Global Health Equity.JCO global oncology · 2025Review
- Psychiatric Disorders in Survivors of Pediatric Acute Lymphoblastic Leukemia in India.Indian journal of pediatrics · 2025Article
- Long-term Follow-up for Survivors of Childhood Cancer in Saudi Arabia: A Multicenter Cross-Sectional Study.Health services insights · 2025Article
- Cancer survivorship in low- and middle-income countries: challenges, needs, and emerging support strategies.Frontiers in public health · 2025Review
- Self-Reported Late Effects in Childhood Cancer Survivors in Kenya.African health sciences · 2024Article
- Children with Cancer: Shared Care and Transition of Care.Indian journal of pediatrics · 2023Review
- Is Methotrexate Ototoxic? Investigating the Ototoxic Late Effects of Pediatric Cancer Treatment.American journal of audiology · 2023Article
- A Retrospective Study of Renal Growth Changes after Proton Beam Therapy for Pediatric Malignant Tumor.Current oncology (Toronto, Ont.) · 2023Article
- Long-Term Outcomes in Survivors of Childhood Cancer: A 30-Year Experience From India.JCO global oncology · 2022Article
- Metabolic syndrome in childhood cancer survivors: delta BMI a risk factor in lower-middle-income countries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Precursor B-cell acute lymphoblastic leukaemia-a global view.British journal of haematology · 2022Review
- Growth patterns of survivors of retinoblastoma treated with ophthalmic artery chemosurgery.PloS one · 2018Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesWith improved survival of childhood cancer patients, the number of long-term cancer survivors is increasing. Some studies have assessed the long-term morbidity after childhood cancer treatment in the developing countries. This study was conducted to assess the spectrum of late effects of cancer treatment in paediatric cancer survivors.
methodsEvaluation of the first 300 patients who completed five years of follow up in the after treatment completion clinic was done. Details of primary diagnosis, treatment received and current clinical status were noted. The spectrum of late effects was ascertained by appropriate investigations.
resultsHaematological malignancies comprised 25 per cent of total cases. Most common primary diagnosis comprised acute lymphoblastic leukaemia, retinoblastoma and Hodgkin's lymphoma. The median age at evaluation and follow up was 14 and 8.5 yr, respectively. Twenty three per cent (69) of the survivors had a minimal disability (growth retardation or underweight), 13 per cent (39) had moderate disabilities needing medical attention (hepatitis B surface antigen positive, myocardial dysfunction, azoospermia and hypothyroidism), while two per cent had major/life-threatening disabilities (mental retardation, liver disease and mortality). Eleven patients relapsed on follow up, of those five patients expired. Two second malignancies were recorded during the period of follow up. INTERPRETATION &
conclusionsLate effects were of concern; however, severe disability (Grade 3-5) was seen in only two per cent survivors. Lifelong follow up of childhood cancer survivors is required to assess cancer-related morbidity, occurrence of a secondary neoplasm, to facilitate timely diagnosis and to implement remedial or preventive interventions to optimize health outcomes. Awareness towards the existence of late effects of cancer therapy is required among parents, patients and health professionals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.