Evidence map›Paper›PMID 29264963›Full record

ReviewTranscription2018

Breaking the mold: structures of the RNA polymerase I transcription complex reveal a new path for initiation.

Ashleigh J Jackobel, Yan Han, Yuan He, Bruce A Knutson

Open access · hybridAbstract readReview
In one paragraph

Review in Transcription, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ashleigh J Jackobela SUNY Upstate Medical University , Department of Biochemistry and Molecular Biology , 750 East Adams Street, Syracuse , NY 13210.
Yan Hanb Northwestern University , Department of Molecular Biosciences , 2205 Tech Drive, Evanston , IL 60208.ORCID 0000-0002-1207-7756
Yuan Heb Northwestern University , Department of Molecular Biosciences , 2205 Tech Drive, Evanston , IL 60208.ORCID 0000-0002-1455-3963
Bruce A Knutsona SUNY Upstate Medical University , Department of Biochemistry and Molecular Biology , 750 East Adams Street, Syracuse , NY 13210.
Northwestern University · USSUNY Upstate Medical University · US

Funding

Molecular mechanism of RNA polymerase I transcription and dysregulation in cancerK22CA184235 · NCI · UPSTATE MEDICAL UNIVERSITY · PI KNUTSON, BRUCE ALAN · 2014 to 2016
$634k
NCI NIH HHS K22 CA184235
6 · The paper itself

Abstract

While structures of the RNA polymerase (Pol) II initiation complex have been resolved and extensively studied, the Pol I initiation complex remained elusive. Here, we review the recent structural analyses of the yeast Pol I transcription initiation complex that reveal several unique and unexpected Pol I-specific properties.

Indexed as

Transcription Initiation, GeneticRNA Polymerase ISaccharomyces cerevisiaeRNA Polymerase ICore Factorpre-initiation complexpromoter openingpromoter recognitionRNA polymerase Itranscription initiation

Identifiers

PMID29264963
PMCPMC6104693
OpenAlexW2776494466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.