Evidence map›Paper›PMID 29264766›Full record

ArticleIn vitro cellular & developmental biology. Animal2018

Caspase-dependent apoptosis induced by two synthetic halogenated flavanones, 3',7-dichloroflavanone and 3',6-dichloroflavanone, on human breast and prostate cancer cells.

Maliheh Safavi, Raheleh Shakeri, Sussan Kabudanian Ardestani, Jamshid Davoodi, Soheila Ajdary, Alireza Foroumadi

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Maliheh SafaviDepartment of Biotechnology, Iranian Research Organization for Science and Technology, 13353-5111, Tehran, Iran. msafavi@ut.ac.ir.
Raheleh ShakeriDepartment of Biological Science, Faculty of Science, University of Kurdistan, Sanandaj, Iran.
Sussan Kabudanian ArdestaniInstitute of Biochemistry and Biophysics, University of Tehran, PO Box 13145-1384, Tehran, Iran.
Jamshid DavoodiInstitute of Biochemistry and Biophysics, University of Tehran, PO Box 13145-1384, Tehran, Iran.
Soheila AjdaryDepartment of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Alireza ForoumadiDepartment of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran.
University of Tehran · IRIranian Research Organization for Science and Technology · IRPasteur Institute of Iran · IRTehran University of Medical Sciences · IRUniversity of Kurdistan · IR

Funding

Iran National Science Foundation 89001967
6 · The paper itself

Abstract

The destruction of cancer cells with chemotherapeutic agents is normally achieved through apoptosis. We previously introduced two synthetic halogenated flavanone derivatives, 3

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsCaspase 3Caspase 8Caspase 9Cell Line, TumorCell SurvivalEtoposideFemaleFlavanonesHumansMalePoly (ADP-Ribose) Polymerase-1Prostatic NeoplasmsAntineoplastic AgentsCASP8 protein, humanCASP9 protein, humanCaspase 3Caspase 8Caspase 9EtoposideFlavanonesPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1ApoptosisBreast cancerFlavanoneProstate cancer

Identifiers

PMID29264766
OpenAlexW2776483277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.