ArticleSurgical endoscopy2018
The fourth space surgery: endoscopic subserosal dissection for upper gastrointestinal subepithelial tumors originating from the muscularis propria layer.
Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- [Diagnosis and Management of Asymptomatic Upper Gastrointestinal Subepithelial Lesions].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026Guideline
- Endoscopic Full-Thickness Resection for Gastrointestinal Subepithelial and Epithelial Neoplasia: Current Status, Indications, and Technical and Oncological Challenges-A Multispecialty Perspective.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Endoscopic tunneling and subserosal dissection using a natural orifice transluminal endoscopic surgery approach for a gastrointestinal stromal tumor.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Clinical efficacy of endoscopic resection for subepithelial tumors in the esophagogastric junction and gastric cardia: an observational study.Clinical endoscopy · 2026Article
- Nationwide Multicenter Study of Advanced Endoscopic Resection and Malignant Risk Model for Gastric Myogenic Tumors (GASTRO Trial).Life (Basel, Switzerland) · 2026Article
- Efficacy and safety of endoscopic subserosal dissection treatment for gastrointetinal submucosal tumors in the upper gastrointestinal tract.BMC surgery · 2024Article
- Endoscopic Treatment for Gastric Subepithelial Tumor.Journal of gastric cancer · 2024Review
- Snare traction and endoscopic suturing can improve endoscopic management of gastrointestinal stromal tumors at the gastric greater curvature.Endoscopy · 2023Article
- Gastric endoscopic muscularis dissection using a partial intramuscular injection technique.Endoscopy · 2023Article
- Risk factors of perforation in gastric stromal tumors during endoscopic resection: a retrospective case-control study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023Article
- Endoscopic adventitial dissection of a rectal GI stromal cell tumor.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Endoscopic subserosal dissection for a GI stromal tumor.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Endoscopic subserosal dissection for gastric tumors: 18 cases in a single center.Surgical endoscopy · 2022Observational
- Successful endoscopic full-thickness resection of an exophytic subepithelial lesion with double scope traction technique.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2022Article
- Traction method for endoscopic subserosal dissection.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2020Article
- Sclerotherapy needle injections can expand the subserosal and muscularis propria layers and cause a stable mucosal lift in ESD/EMR patients.Surgical endoscopy · 2019Article
- Perioperative and long-term outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma with well-preserved liver function and cirrhotic background: a propensity score matching study.Surgical endoscopy · 2019Article
- Diagnostic yield of deep biopsy via endoscopic submucosal dissection for the diagnosis of upper gastrointestinal subepithelial tumors: a systematic review and meta-analysis.Annals of gastroenterologyArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsWe developed a novel method of endoscopic subserosal dissection (ESSD) for removal of subepithelial tumors (SETs) originating from the muscularis propria (MP) layer in the upper gastrointestinal (GI) tract. The aim of this study was to evaluate the efficacy, safety, and clinical outcome of this method.
methodsEleven patients with upper GI SETs originating from the MP layer were treated by ESSD between October 2016 and March 2017. ESSD technique consists of six major procedures: (1) incising the mucosal and submucosal layer around the lesion and exposing MP layer; (2) continuous injection was performed while the injection needle slowly moved from the MP layer toward the subserosal layer; (3) incising MP layer; (4) subserosal injection was performed to further separate the serosa from the MP layer; (5) the mucosa, submucosa, and MP layer including SET were carefully dissected en bloc; and (6) closure of the gastric-wall defect with endoscopic techniques. Primary outcome including clinical procedural success and procedure-related adverse events were documented.
resultsESSD was successfully performed in 11 patients. The complete resection rate was 100%, and the mean operation time was 51 (range 22-76) min. The mean resected lesion size was 27 (range 15-40) mm. Pathological diagnosis of these lesions included gastrointestinal stromal tumors (8/11), heterotopic pancreas (1/11), hamartoma (1/11), and leiomyoma (1/11). The small perforations occurred in two patients (4 × 4 and 5 × 5 mm, respectively) during the operation. All perforations and defects were closed successfully by endoscopic techniques. No GI bleeding, peritonitis, abdominal abscess, and other adverse events were observed. No lesion residual or recurrence was found during the follow-up period (mean 18 weeks; range 10-29 weeks).
conclusionESSD seems to be an efficacious, safe, and minimally invasive treatment for patients with upper GI SETs originating from the MP layer, making it possible to resect deep lesions, provide precise pathological diagnosis, and maintain the integrity of serosa.
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