Evidence map›Paper›PMID 29264635›Full record

ArticleEuropean radiology2018

Fat necrosis after abdominal surgery: A pitfall in interpretation of FDG-PET/CT.

Tima Davidson, Eyal Lotan, Eyal Klang, Johnatan Nissan, Jeffrey Goldstein, Elinor Goshen, Simona Ben-Haim, Sara Apter, Bar Chikman

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Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Molecular imaging and radionuclide therapy · 2026
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  3. Radiology. Imaging cancer · 2023
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  13. Nuclear medicine and molecular imaging · 2020
    Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Tima DavidsonDepartment of Nuclear Medicine, Chaim Sheba Medical Center, 5265601, Tel Hashomer, Israel. tima.davidson@sheba.health.gov.il.
Eyal LotanSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Eyal KlangSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Johnatan NissanTechnion - Israel Institute of Technology, Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel. johnatan.n@gmail.com.
Jeffrey GoldsteinDepartment of Radiation Oncology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Elinor GoshenDepartment of Nuclear Medicine, Chaim Sheba Medical Center, 5265601, Tel Hashomer, Israel.
Simona Ben-HaimDepartment of Nuclear Medicine, Chaim Sheba Medical Center, 5265601, Tel Hashomer, Israel.
Sara ApterSackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Bar ChikmanDivision of Surgery, Assaf Harofeh Medical Center, Zerifin, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe describe FDG-PET/CT findings of postoperative fat necrosis in patients following abdominal surgery, and evaluate their changes in size and FDG uptake over time.

methodsFDG-PET/CT scans from January 2007-January 2016 containing the term 'fat necrosis' were reviewed. Lesions meeting radiological criteria of fat necrosis in patients with prior abdominal surgery were included.

resultsForty-four patients, 30 males, mean age 68.4 ± 11.0 years. Surgeries: laparotomy (n=37; 84.1 %), laparoscopy (n=3; 6.8 %), unknown (n=4; 9.1 %). CTs of all lesions included hyperdense well-defined rims surrounding a heterogeneous fatty core. Sites: peritoneum (n=34; 77 %), omental fat (n=19; 43 %), subcutaneous fat (n=8; 18 %), retroperitoneum (n=2; 5 %). Mean lesion long axis: 33.6±24.9 mm (range: 13.0-140.0). Mean SUVmax: 2.6±1.1 (range: 0.6-5.1). On serial CTs (n=34), lesions decreased in size (p=0.022). Serial FDG-PET/CT (n=24) showed no significant change in FDG-avidity (p=0.110). Mean SUVmax did not correlate with time from surgery (p=0.558) or lesion size (p=0.259).

conclusionPostsurgical fat necrosis demonstrated characteristic CT features and may demonstrate increased FDG uptake. However, follow-up of subsequent imaging scans showed no increases in size or FDG-avidity. Awareness of this entity is important to avoid misinterpretation of findings as recurrent cancer. KEY POINTS: • Postsurgical fat necrosis may mimic cancer in FDG-PET/CT. • Follow-up of fat necrosis showed no increase in FDG intensity. • CT follow-up showed a decrease in lesion size. • FDG uptake did not correlate with time lapsed from surgery.

Indexed as

AbdomenAbdominal NeoplasmsAdultAgedAged, 80 and overDiagnosis, DifferentialFat NecrosisFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPositron Emission Tomography Computed TomographyPostoperative ComplicationsRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsAbdominalFat necrosisFDG PET-CTPitfallPostoperative

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.