Evidence map›Paper›PMID 29264515›Full record

ArticleJournal of the Endocrine Society2017

Longitudinal Assessment of PTH in Community-Dwelling Older Women-Elevations Are Not Associated With Mortality.

David Buchebner, Linnea Malmgren, Anders Christensson, Fiona McGuigan, Paul Gerdhem, Martin Ridderstråle, Kristina Åkesson

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Reduced kidney function is associated with BMD, bone loss and markers of mineral homeostasis in older women: a 10-year longitudinal study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David BuchebnerDepartment of Clinical Science Malmö, Clinical and Molecular Osteoporosis Research Unit, Lund University, Department of Orthopaedics, Skåne University Hospital, 221 00 Malmö, Sweden.
Linnea MalmgrenDepartment of Clinical Science Malmö, Clinical and Molecular Osteoporosis Research Unit, Lund University, Department of Orthopaedics, Skåne University Hospital, 221 00 Malmö, Sweden.
Anders ChristenssonDepartment of Nephrology, Skåne University Hospital, 214 28 Malmö, Sweden.
Fiona McGuiganDepartment of Clinical Science Malmö, Clinical and Molecular Osteoporosis Research Unit, Lund University, Department of Orthopaedics, Skåne University Hospital, 221 00 Malmö, Sweden.
Paul GerdhemDepartment of Clinical Science, Intervention and Technology, Karolinska Institute, Department of Orthopaedics, Karolinska University Hospital, 171 77 Stockholm, Sweden.
Martin RidderstråleDepartment of Endocrinology, Clinical Obesity Research, Skåne University Hospital 214 28, Malmö, Sweden.
Kristina ÅkessonDepartment of Clinical Science Malmö, Clinical and Molecular Osteoporosis Research Unit, Lund University, Department of Orthopaedics, Skåne University Hospital, 221 00 Malmö, Sweden.
Skåne University Hospital · SEKarolinska Institutet · SELund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextIn older women, the magnitude of elevated parathyroid hormone (PTH) and its consequence is unclear.

objectiveTo describe normal PTH profiles over time and the association with mortality. DESIGN AND

participantsThere were 1044 community-dwelling women in the Malmö Osteoporosis Prospective Risk Assessment cohort (OPRA) who attended baseline (age 75 years). Follow-ups were attended by 715 (age 80 years) and 382 (age 85 years).

main outcome measuresPTH, estimated glomerular filtration rate (eGFR), 25-hydroxyvitamin D (25OHD) and mortality.

resultsAt age 75 years, PTH levels for most (n = 877, 88%) were within the normal reference range (NRR) (

conclusionsMost women remained within normal PTH ranges despite large increases of up to 50%. PTH elevated above normal is not independently associated with mortality; impaired kidney function and low 25OHD status may be more prognostic in the very old.

Indexed as

elderly womenkidney functionmortalityPTHvitamin D

Identifiers

PMID29264515
PMCPMC5686779
OpenAlexW2606426629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.