Evidence map›Paper›PMID 29264471›Full record

ArticleJournal of the Endocrine Society2017

Pachydermoperiostosis Masquerading as Acromegaly.

Munira M Karimova, Zamira Yu Halimova, Yulduz M Urmanova, Márta Korbonits, Treena Cranston, Ashley B Grossman

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Endocrine Alterations in Patients With Pachydermoperiostosis.The Journal of clinical endocrinology and metabolism · 2025
    Article
  2. Article
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  6. Pachydermoperiostosis: a rare mimicker of acromegaly.Endocrinology, diabetes & metabolism case reports · 2017
    Article
  7. Complete form of pachydermoperiostosis.Anais brasileiros de dermatologia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Munira M KarimovaDepartment of Neuroendocrinology, Center of the Scientific and Clinical Study of Endocrinology, Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan 100140.
Zamira Yu HalimovaDepartment of Neuroendocrinology, Center of the Scientific and Clinical Study of Endocrinology, Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan 100140.
Yulduz M UrmanovaDepartment of Neuroendocrinology, Center of the Scientific and Clinical Study of Endocrinology, Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan 100140.
Márta KorbonitsCentre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Treena CranstonDepartment of Clinical Genetics, Churchill Hospital, and.
Ashley B GrossmanOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OXE 7LE, United Kingdom.
Tashkent Pediatric Medical Institute · UZChurchill Hospital · GBQueen Mary University of London · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAcromegaly usually is suspected on clinical grounds. Biochemical confirmation is required to optimize therapy, but there are other differential diagnoses. CASE DESCRIPTION: We describe a 24-year-old Uzbek man who presented with many clinical symptoms and signs of apparent acromegaly. On examination, the patient showed a rugose folding of his scalp, with the formation of tender, painful, rough skin folds in the parietal-occipital region, resembling cerebral gyri (

conclusionThe condition of pachydermoperiostosis may masquerade as acromegaly but is a genetic disorder, usually autosomal recessive, leading to elevated prostaglandin E2 levels. This is an important, albeit rare, differential diagnosis of acromegaly.

Indexed as

acromegalydiagnosispachydermoperiostosispulmonary hypertrophic osteoarthropathy

Identifiers

PMID29264471
PMCPMC5686560
OpenAlexW2788976368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.