Evidence map›Paper›PMID 29264465›Full record

ArticleJournal of the Endocrine Society2017

Metabolic Concomitants of Obese and Nonobese Women With Features of Polycystic Ovarian Syndrome.

Jocelyne Matar Boumosleh, Scott M Grundy, Jennifer Phan, Ian J Neeland, Alice Chang, Gloria Lena Vega

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Implicating androgen excess in propagating metabolic disease in polycystic ovary syndrome.Therapeutic advances in endocrinology and metabolism · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jocelyne Matar BoumoslehThe Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
Scott M GrundyThe Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
Jennifer PhanThe Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
Ian J NeelandDepartment of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
Alice ChangDepartment of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
Gloria Lena VegaThe Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390.
The University of Texas Southwestern Medical Center · USVeterans Health Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextPolycystic ovarian syndrome (PCOS) is often associated with obesity and diabetes.

objectiveThe present study measured body fat distribution and metabolic risk factors in women with features of PCOS.

designCross-sectional, multiethnic study of cardiovascular risks.

settingGeneral community. STUDY

participants145 PCOS and 344 non-PCOS women. EXPOSURE MEASURES: Body composition by dual x-ray absorptiometry; abdominal fat masses measured by magnetic resonance imaging and hepatic triglyceride by magnetic resonance spectroscopy. OUTCOMES MEASURES: Body composition, liver fat content, homeostatic model assessment for insulin resistance (HOMA-IR), revised, and metabolic syndrome components.

resultsPCOS women had a higher free androgen index compared with the non-PCOS women. Nonobese PCOS and non-PCOS women had a similar body fat content and distribution, HOMA-IR, and hepatic triglyceride content. Obese PCOS women had a similar total body fat percentage compared with their non-PCOS counterparts (41.4% and 41.4% respectively). Both obese groups had similar intraperitoneal fat (1.4% of total body mass in PCOS vs 1.4% in non-PCOS). However, obese PCOS women had a greater ratio of truncal/lower body fat (1.42 vs 1.27;

conclusionsBoth obese and nonobese women with PCOS features had a greater free androgen index compared with non-PCOS women, but neither had greater intraperitoneal fat or abnormal lipid levels. Obese, but not nonobese, women with PCOS had a greater truncal/lower extremity fat ratio, HOMA-IR, and liver triglyceride content.

Identifiers

PMID29264465
PMCPMC5695651
OpenAlexW2766932569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.