Evidence map›Paper›PMID 29264081›Full record

ArticleJournal of general and family medicine2017

Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis.

Yuki Onuma, Masayuki Oki, Masamichi Komatsu, Sho Ishitani, Kei Kijima, Ryuki Fukuda, Yusuke Moriya, Hideki Ozawa, Atsushi Takagi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of general and family medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuki OnumaDivision of General Internal Medicine Department of Medicine Tokai University Oiso Hospital Isehara Kanagawa Japan.ORCID 0000-0001-7160-9380
Masayuki OkiDivision of General Internal Medicine Department of Medicine Tokai University Hospital Isehara Kanagawa Japan.
Masamichi KomatsuDivision of General Internal Medicine Department of Medicine Tokai University Oiso Hospital Isehara Kanagawa Japan.
Sho IshitaniDivision of General Internal Medicine Department of Medicine Tokai University Oiso Hospital Isehara Kanagawa Japan.
Kei KijimaDivision of General Internal Medicine Department of Medicine Tokai University Oiso Hospital Isehara Kanagawa Japan.
Ryuki FukudaDivision of General Internal Medicine Department of Medicine Tokai University Oiso Hospital Isehara Kanagawa Japan.
Yusuke MoriyaDepartment of Neurology Tokai University Oiso Hospital Isehara Kanagawa Japan.
Hideki OzawaDivision of General Internal Medicine Family Medicine Program Tokai University Hospital Isehara Kanagawa Japan.
Atsushi TakagiDivision of General Internal Medicine Department of Medicine Tokai University Hospital Isehara Kanagawa Japan.
Shonan Oiso Hospital · JPTokai University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 82-year-old woman with primary biliary cholangitis was diagnosed with an irreversible neurological disorder, caused by metronidazole (MNZ)-induced encephalopathy. Although the disorder is a reversible pathological condition, in rare cases, it can cause serious sequelae or could even be fatal. Therefore, medications should be administered carefully, particularly in patients who require long-term administration of large doses or those with liver dysfunction.

Indexed as

encephalopathyirreversibilityliver dysfunctionmetronidazole

Identifiers

PMID29264081
PMCPMC5729387
OpenAlexW2718136540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.