ArticleProceedings. IEEE International Conference on Bioinformatics and Biomedicine2016
Analysis of Temporal Constraints in Qualitative Eligibility Criteria of Cancer Clinical Studies.
Article in Proceedings. IEEE International Conference on Bioinformatics and Biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Deep Learning Approach to Parse Eligibility Criteria in Dietary Supplements Clinical Trials Following OMOP Common Data Model.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Article
- Comparing the Study Populations in Dietary Supplement and Drug Clinical Trials for Metabolic Syndrome and Related Disorders.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Clinical studies, especially randomized controlled trials, generate gold-standard medical evidence. However, the lack of population representativeness of clinical studies has hampered their generalizability to the real-world population. Overly restrictive qualitative criteria are often applied to exclude patients. In this work, we develop a lexical-pattern-based tool to structure qualitative eligibility criteria with temporal constraints, with which we analyzed over 10,800 cancer clinical studies. Our results showed that restrictive temporal constraints are often applied on qualitative criteria in cancer studies, limiting the generalizability of their results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.