Evidence map›Paper›PMID 29263882›Full record

ArticleNPJ vaccines2017

Humoral protection against mosquito bite-transmitted

Brandon K Sack, Sebastian A Mikolajczak, Matthew Fishbaugher, Ashley M Vaughan, Erika L Flannery, Thao Nguyen, Will Betz, Mary Jane Navarro, Lander Foquet, Ryan W J Steel and 14 more

Abstract read
In one paragraph

Article in NPJ vaccines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
  2. Article
  3. Protection from malaria infection using liver-targeted siRNA.Molecular therapy. Methods & clinical development · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Molecular therapy. Methods & clinical development · 2022
    Article
  14. Article
  15. AiScience · 2022
    Article
  16. Article
  17. Vaccines · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Brandon K SackCenter for Infectious Disease Research, Seattle, WA USA.
Sebastian A MikolajczakCenter for Infectious Disease Research, Seattle, WA USA.
Matthew FishbaugherCenter for Infectious Disease Research, Seattle, WA USA.
Ashley M VaughanCenter for Infectious Disease Research, Seattle, WA USA.
Erika L FlanneryCenter for Infectious Disease Research, Seattle, WA USA.
Thao NguyenCenter for Infectious Disease Research, Seattle, WA USA.
Will BetzCenter for Infectious Disease Research, Seattle, WA USA.
Mary Jane NavarroCenter for Infectious Disease Research, Seattle, WA USA.
Lander FoquetCenter for Infectious Disease Research, Seattle, WA USA.
Ryan W J SteelCenter for Infectious Disease Research, Seattle, WA USA.
Zachary P BillmanDepartments of Laboratory Medicine and Microbiology and the Center for Emerging and Re-emerging Infectious Diseases, University of Washington, Seattle, WA USA.
Sean C MurphyCenter for Infectious Disease Research, Seattle, WA USA.
Stephen L HoffmanSanaria, Inc., Rockville, MD USA.
Sumana ChakravartySanaria, Inc., Rockville, MD USA.
B Kim Lee SimSanaria, Inc., Rockville, MD USA.
Marije BehetRadboud University, Nijmegen, The Netherlands.
Isaie J ReulingRadboud University, Nijmegen, The Netherlands.
Jona WalkRadboud University, Nijmegen, The Netherlands.
Anja ScholzenRadboud University, Nijmegen, The Netherlands.
Robert W SauerweinRadboud University, Nijmegen, The Netherlands.
Andrew S IshizukaNational Institutes of Health, Bethesda, MD USA.
Barbara FlynnNational Institutes of Health, Bethesda, MD USA.
Robert A SederNational Institutes of Health, Bethesda, MD USA.
Stefan H I KappeCenter for Infectious Disease Research, Seattle, WA USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Development of Pre-Erythrocytic Malaria Vaccines and antibodiesZIAAI005107 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SEDER, ROBERT A · 2010 to 2025
$20.7M
Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Mechanisms of antibody protection in pre-erythrocytic and blood stage malariaF32AI114113 · NIAID · SEATTLE BIOMEDICAL RESEARCH INSTITUTE · PI WILDER, BRANDON KEITH · 2014 to 2016
$164k
NIAID NIH HHS F32 AI114113NIGMS NIH HHS T32 GM007171NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

A malaria vaccine that prevents infection will be an important new tool in continued efforts of malaria elimination, and such vaccines are under intense development for the major human malaria parasite

Identifiers

PMID29263882
PMCPMC5634440

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.