Evidence map›Paper›PMID 29263859›Full record

ArticleNPJ vaccines2016

Karuppiah Muthumani, Bryan D Griffin, Sangya Agarwal, Sagar B Kudchodkar, Emma L Reuschel, Hyeree Choi, Kimberly A Kraynyak, Elizabeth K Duperret, Amelia Anne Keaton, Christopher Chung and 19 more

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 136 citations in OpenAlex.

  1. Trial
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  8. Article
  9. Review
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  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Future vaccines in pregnancy.Best practice & research. Clinical obstetrics & gynaecology · 2021
    Review
  18. Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine.The New England journal of medicine · 2021
    Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 6 institutions in 3 countries.

Karuppiah MuthumaniThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Bryan D GriffinSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 3R2.
Sangya AgarwalThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.ORCID 0000-0003-4272-515X
Sagar B KudchodkarThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Emma L ReuschelThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Hyeree ChoiThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Kimberly A KraynyakInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Elizabeth K DuperretThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Amelia Anne KeatonDivision of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Christopher ChungThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Yinho K KimThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Stephanie A BoothSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 3R2.
Trina RacineSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 3R2.
Jian YanInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Matthew P MorrowInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Jingjing JiangInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Brian LeeInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Stephanie RamosInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Kate E BroderickInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Charles C ReedInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Amir S KhanInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Laurent HumeauInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Kenneth E UgenDepartment of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, FL, USA.ORCID 0000-0002-7797-2049
Young K ParkGeneOne Life Science Inc., Teheran-Ro, Gangnam-Gu, Seoul, Korea.
Joel N MaslowGeneOne Life Science Inc., Teheran-Ro, Gangnam-Gu, Seoul, Korea.
Niranjan Y SardesaiInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
J Joseph KimInovio Pharmaceuticals Inc., Plymouth Meeting, PA, USA.
Gary P KobingerSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada R3E 3R2.
David B WeinerThe Wistar Institute, 3601 Spruce Street, Philadelphia, PA, USA.
Inovio Pharmaceuticals (United States) · USThe Wistar Institute · USPublic Health Agency of Canada · CAKolon Life Science (South Korea) · KRChildren's Hospital of Philadelphia · USUniversity of South Florida · US

Funding

Development of a Universal Influenza Seasonal VaccineR01AI092843 · NIAID · WISTAR INSTITUTE · PI WEINER, DAVID B. · 2010 to 2014
$3.0M
NIAID NIH HHS R01 AI092843
6 · The paper itself

Abstract

Significant concerns have been raised owing to the rapid global spread of infection and disease caused by the mosquito-borne Zika virus (ZIKV). Recent studies suggest that ZIKV can also be transmitted sexually, further increasing the exposure risk for this virus. Associated with this spread is a dramatic increase in cases of microcephaly and additional congenital abnormalities in infants of ZIKV-infected mothers, as well as a rise in the occurrence of Guillain Barre' syndrome in infected adults. Importantly, there are no licensed therapies or vaccines against ZIKV infection. In this study, we generate and evaluate the

Identifiers

PMID29263859
PMCPMC5707885
OpenAlexW2551325974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.