An efficient cell free enzyme-based total synthesis of a meningococcal vaccine candidate.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

1. Synthetic Glycans to Improve Current Glycoconjugate Vaccines and Fight Antimicrobial Resistance.Chemical reviews · 2022
   Review
2. Carbohydrate based meningococcal vaccines: past and present overview.Glycoconjugate journal · 2021
   Review
3. Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones frommBio · 2021
   Article
4. Elucidating the Structural and Minimal Protective Epitope of the Serogroup X Meningococcal Capsular Polysaccharide.Frontiers in molecular biosciences · 2021
   Article
5. An enzyme-based protocol for cell-free synthesis of nature-identical capsular oligosaccharides fromThe Journal of biological chemistry · 2020
   Article
6. Leloir Glycosyltransferases in Applied Biocatalysis: A Multidisciplinary Approach.International journal of molecular sciences · 2019
   Review
7. A New Family of Capsule Polymerases Generates Teichoic Acid-Like Capsule Polymers in Gram-Negative Pathogens.mBio · 2018
   Article
8. Potential targets for next generation antimicrobial glycoconjugate vaccines.FEMS microbiology reviews · 2018
   Review
9. Engineering a new generation of carbohydrate-based vaccines.Current opinion in chemical engineering · 2018
   Article
10. Meningococcal Vaccines: Current Status and Emerging Strategies.Vaccines · 2018
    Review
11. Efficient solid-phase synthesis of meningococcal capsular oligosaccharides enables simple and fast chemoenzymatic vaccine production.The Journal of biological chemistry · 2018
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

11 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract