Evidence map›Paper›PMID 29263822›Full record

ArticleNPJ genomic medicine2017

Precision Military Medicine: Conducting a multi-site clinical utility study of genomic and lifestyle risk factors in the United States Air Force.

Susan K Delaney, Ruth Brenner, Tara J Schmidlen, Michael P Dempsey, Kim E London, Erynn S Gordon, Mark Bellafante, Ashley Nasuti, Laura B Scheinfeldt, Kaveri D Rajula and 4 more

Open access · goldAbstract read
In one paragraph

Article in NPJ genomic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Susan K DelaneyCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Ruth BrennerAir Force Medical Support Agency, Defense Health Headquarters, Falls Church, VA 22042 USA.
Tara J SchmidlenCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Michael P DempseyAir Force Medical Support Agency, Defense Health Headquarters, Falls Church, VA 22042 USA.
Kim E LondonAir Force Research Laboratory, Institutional Review Board, 711 HPW/IR, Wright-Patterson AFB, OH 45433 USA.
Erynn S GordonCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Mark BellafanteCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Ashley NasutiCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Laura B ScheinfeldtCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Kaveri D RajulaCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Leo JoseCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Joseph P JarvisCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Norman P GerryCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Michael F ChristmanCoriell Institute for Medical Research, 403 Haddon Avenue, Camden, NJ 08103 USA.
Coriell Institute For Medical Research · USDefense Health Agency · USGenomics Medicine (Ireland) · IEHuman Genome Sciences (United States) · USUnited States Air Force Research Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following several years enrolling disease-specific and otherwise healthy cohorts into the Coriell Personalized Medicine Collaborative, a prospective study aimed at evaluating the clinical utility of personal genomic information for common complex disease and pharmacogenomics, the Coriell Personalized Medicine Collaborative expanded to create a military cohort, specifically, the United States Air Force. Initial recruitment focused on Air Force Medical Service personnel and later expanded to include all Active Duty Air Force members and beneficiaries. Now in its 6th year, the study has produced a wide variety of insights, including optimal study design for military-sponsored genomic research, and discussion on genetic information sharing between and amongst Air Force study participants, civilian and military researchers, and the United States Department of Defense. Over the longer term, analyses will further contribute to the development of policies and processes relevant to clinical decision support and data sharing within the US military, and on-going work with the Air Force Medical Service sub-cohort will generate critical insights into how best to deploy useful genomic information in clinical care. Here we discuss challenges faced and critical success factors for military-civilian collaborations around genomic research.

Identifiers

PMID29263822
PMCPMC5677975
OpenAlexW2578251598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.