Evidence map›Paper›PMID 29263428›Full record

ArticleScientific reports2017

Deciphering the emergence, genetic diversity and evolution of classical swine fever virus.

Liliam Rios, Liani Coronado, Dany Naranjo-Feliciano, Orlando Martínez-Pérez, Carmen L Perera, Lilian Hernandez-Alvarez, Heidy Díaz de Arce, José I Núñez, Llilianne Ganges, Lester J Pérez

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liliam RiosUniversity of New Brunswick, Saint John, New Brunswick, E2L4L5, Canada.
Liani CoronadoCentro Nacional de Sanidad Agropecuaria (CENSA), La Habana, 32700, Cuba.
Dany Naranjo-FelicianoCentro Nacional de Sanidad Agropecuaria (CENSA), La Habana, 32700, Cuba.
Orlando Martínez-PérezUniversidad de las Ciencias Informáticas (UCI), La Habana, Cuba.
Carmen L PereraCentro Nacional de Sanidad Agropecuaria (CENSA), La Habana, 32700, Cuba.
Lilian Hernandez-AlvarezCentro Nacional de Sanidad Agropecuaria (CENSA), La Habana, 32700, Cuba.
Heidy Díaz de ArceHospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH, Buenos Aires, Argentina.
José I NúñezIRTA-CReSA. Centre de Recerca en Sanitat Animal, Barcelona, 08193, Spain.
Llilianne GangesIRTA-CReSA. Centre de Recerca en Sanitat Animal, Barcelona, 08193, Spain.
Lester J PérezDalhousie University, Dalhousie Medicine New Brunswick, Saint John, New Brunswick, E2L4L5, Canada. lester.perez@dal.ca.ORCID 0000-0002-5717-5181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical swine fever (CSF) is one of the most important infectious diseases causing significant economic losses. Its causal agent, CSF virus (CSFV), is a member of the Pestivirus genus included into the Flaviviridae family. Previous molecular epidemiology studies have revealed the CSFV diversity is divided into three main genotypes and different subgenotypes. However, the classification system for CSFV has not yet been harmonized internationally. Similarly, the phylogeny and evolutionary dynamics of CSFV remain unclear. The current study provides novel and significant insights into the origin, diversification and evolutionary process of CSFV. In addition, the best phylogenetic marker for CSFV capable of reproducing the same phylogenetic and evolutionary information as the complete viral genome is characterized. Also, a reliable cut-off to accurately classify CSFV at genotype and subgenotype levels is established. Based on the time for the most recent common ancestor (tMRCA) reconstruction and cophylogenetic analysis, it was determined that CSFV emerged around 225 years ago when the Tunisian Sheep Virus jumped from its natural host to swine. CSFV emergence was followed by a genetic expansion in three main lineages, driven by the action of positive selection pressure and functional divergence, as main natural forces.

Indexed as

AnimalsBiodiversityBiological EvolutionClassical Swine FeverClassical Swine Fever VirusGenetic VariationGenome, ViralGenotypeMolecular EpidemiologyPhylogenySwine

Identifiers

PMID29263428
PMCPMC5738429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.