ArticleNature communications2017
NAIP/NLRC4 inflammasome activation in MRP8
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Current understanding of the NLRC4 Inflammasome in autoinflammation and enterocolitis.Communications biology · 2026Review
- Review
- Inflammasome protein scaffolds the DNA damage complex during tumor development.Nature immunology · 2024Article
- IRG1/ACOD1 promotes neutrophil reverse migration and alleviates local inflammation.Journal of leukocyte biology · 2024Article
- Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis.Seminars in immunology · 2023Review
- Uncoupled pyroptosis and IL-1β secretion downstream of inflammasome signaling.Frontiers in immunology · 2023Review
- NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.EMBO reports · 2022Article
- [NLRC4 plays a regulatory role in F. nucleatum-induced pyroptosis in macrophages].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis.EMBO reports · 2022Article
- Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis.Frontiers in immunology · 2022Review
- Article
- Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense.Cell reports · 2021Article
- Inflammasomes and adaptive immune responses.Nature immunology · 2021Review
- Sensing soluble uric acid by Naip1-Nlrp3 platform.Cell death & disease · 2021Article
- Inflammasome-Dependent Coagulation Activation in Sepsis.Frontiers in immunology · 2021Review
- N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.Nature communications · 2020Article
- Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases.Cell death & disease · 2020Article
- Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra.Nature microbiology · 2019Article
- Induction of Inflammatory Macrophages in the Gut and Extra-Gut Tissues by Colitis-Mediated Escherichia coli.iScience · 2019Article
- Inflammasomes: Pandora's box for sepsis.Journal of inflammation research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Inflammasomes are cytosolic multiprotein complexes that initiate protective immunity in response to infection, and can also drive auto-inflammatory diseases, but the cell types and signalling pathways that cause these diseases remain poorly understood. Inflammasomes are broadly expressed in haematopoietic and non-haematopoietic cells and can trigger numerous downstream responses including production of IL-1β, IL-18, eicosanoids and pyroptotic cell death. Here we show a mouse model with endogenous NLRC4 inflammasome activation in Lysozyme2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.