Evidence map›Paper›PMID 29263266›Full record

ArticleJournal of virology2018

GalNAc-Specific Soybean Lectin Inhibits HIV Infection of Macrophages through Induction of Antiviral Factors.

Runhong Zhou, Xu Wang, Hang Liu, Le Guo, Qijian Su, He Wang, Theodore Vasiliadis, Wenzhe Ho, Jieliang Li

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A Potential Peptide From Soy Cheese Produced UsingFrontiers in molecular biosciences · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Runhong ZhouSchool of Basic Medical Sciences/State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei, People's Republic of China.
Xu WangDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Hang LiuSchool of Basic Medical Sciences/State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei, People's Republic of China.
Le GuoSchool of Basic Medical Sciences/State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei, People's Republic of China.
Qijian SuCenter for AIDS Research, Ruikang Hospital Affiliated with Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
He WangDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Theodore VasiliadisDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Wenzhe HoSchool of Basic Medical Sciences/State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei, People's Republic of China wenzheho@temple.edu jieliang.li@temple.edu.
Jieliang LiDepartment of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA wenzheho@temple.edu jieliang.li@temple.edu.ORCID https://orcid.org/0000-0001-5033-1930
Temple University · USWuhan University · CNGuangxi University of Chinese Medicine · CN

Funding

Opioids, HIV/HCV and Host Cell Innate ImmunityR01DA022177 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2007 to 2017
$2.9M
Role of miRNAs in Methamphetamine/HIV-mediated Immune ActivationR01DA045568 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2018 to 2022
$2.0M
Methamphetamine, Innate Immunity and HIVR01DA041302 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2016 to 2020
$1.8M
Opioids, Extracellular Vesicles and BBB Innate ImmunityR21DA042373 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2017 to 2018
$436k
Role of Exosomes in the Crosstalk Between Brain Endothelium and HIV NeuroinvasionR21MH109385 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI LI, JIELIANG · 2016 to 2017
$429k
Exosome in Methamphetamine and HIV-associated NeurodegenerationR21DA040329 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI LI, JIELIANG · 2015 to 2016
$427k
Methamphetamine, Brain Endothelial TLR3 Signaling and HIVR03DA036413 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI LI, JIELIANG · 2014 to 2015
$155k
NIDA NIH HHS R01 DA022177NIDA NIH HHS R01 DA041302NIDA NIH HHS R03 DA036413NIDA NIH HHS R21 DA040329NIDA NIH HHS R21 DA042373NIMH NIH HHS R21 MH109385
6 · The paper itself

Abstract

Although it has been shown that some mannose-binding lectins (MBLs) exhibit significant activity against HIV infection, little is known about whether

Indexed as

Anti-HIV AgentsCD4-Positive T-LymphocytesHIV-1HIV Envelope Protein gp120HIV Envelope Protein gp41HIV InfectionsHumansInterferon-betaMacrophagesPhytohemagglutininsPlant LectinsReceptors, CCR5Signal TransductionSoybean ProteinsSTAT Transcription FactorsVirus InternalizationAnti-HIV AgentsCCR5 protein, humangp120 protein, Human immunodeficiency virus 1gp41 protein, Human immunodeficiency virus 1HIV Envelope Protein gp120HIV Envelope Protein gp41Interferon-betaPhytohemagglutininsPlant LectinsReceptors, CCR5soybean lectinSoybean ProteinsSTAT Transcription FactorsGalNAcHIVIFN-βmitogenicitysoybean lectin

Identifiers

PMID29263266
PMCPMC5827391
OpenAlexW2779980451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.