Evidence map›Paper›PMID 29263204›Full record

ArticleJournal of clinical microbiology2018

Parallel Validation of Three Molecular Devices for Simultaneous Detection and Identification of Influenza A and B and Respiratory Syncytial Viruses.

Lifen Ling, Samuel E Kaplan, Juan C Lopez, Jeffrey Stiles, Xuedong Lu, Yi-Wei Tang

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

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  19. Performance and ease of use of a molecular point-of-care test for influenza A/B and RSV in patients presenting to primary care.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  20. A guide to laboratory diagnosis of Corona Virus Disease-19 for the gastroenterologists.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lifen LingDepartment of Laboratory Medicine, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Samuel E KaplanDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Juan C LopezDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jeffrey StilesDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Xuedong LuDepartment of Laboratory Medicine, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Yi-Wei TangDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA tangy@mskcc.org.
Memorial Sloan Kettering Cancer Center · USEighth Affiliated Hospital of Sun Yat-sen UniversitySun Yat-sen University · CN

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Rapid identification of respiratory pathogens, such as influenza virus A (FluA), influenza virus B (FluB), and respiratory syncytial virus (RSV), reduces unnecessary antimicrobial use and enhances infection control practice. We performed a comparative evaluation of three molecular methods: (i) the Aries Flu A/B & RSV, (ii) the Xpert Xpress Flu/RSV, and (iii) the Cobas Flu A/B & RSV assays. The clinical performances of the three methods were evaluated using 200 remnant nasopharyngeal swab (NPS) specimens against a combined reference standard. The limits of detection (LODs) were determined using FluA, FluB, and RSV control strains with known titers. The 95% LODs were between 1.702 and 0.0003 50% tissue culture infective dose (TCID

Indexed as

FemaleHumansInfluenza A virusInfluenza B virusMaleMolecular Diagnostic TechniquesNasopharynxReproducibility of ResultsRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsSensitivity and SpecificityTime Factorshands-on timeinfluenza viruses A and Bmolecular testingrespiratory syncytial virusturnaround time

Identifiers

PMID29263204
PMCPMC5824037
OpenAlexW2779704782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.