Evidence map›Paper›PMID 29263158›Full record

ArticleMolecular and cellular biology2018

Clb6-Cdc28 Promotes Ribonucleotide Reductase Subcellular Redistribution during S Phase.

Xiaorong Wu, Xiuxiang An, Caiguo Zhang, Mingxia Huang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. SiRNA-MediatedInternational journal of medical sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaorong WuDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Xiuxiang AnDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Caiguo ZhangDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Mingxia HuangDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA mingxia.huang@ucdenver.edu.ORCID https://orcid.org/0000-0003-4241-8723
University of Colorado Denver · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
In Vivo Regulation and Inhibition of Ribonucleotide ReductaseR01CA125574 · NCI · UNIVERSITY OF COLORADO DENVER · PI HUANG, MINGXIA · 2008 to 2012
$1.6M
NCI NIH HHS P30 CA046934NCI NIH HHS R01 CA125574
6 · The paper itself

Abstract

A tightly controlled cellular deoxyribonucleotide (deoxynucleoside triphosphate [dNTP]) pool is critical for maintenance of genome integrity. One mode of dNTP pool regulation is through subcellular localization of ribonucleotide reductase (RNR), the enzyme that catalyzes the rate-limiting step of dNTP biosynthesis. In

Indexed as

CDC28 Protein Kinase, S cerevisiaeCyclin BPhosphorylationProtein TransportRibonucleoside Diphosphate ReductaseRibonucleotide ReductasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsS PhaseCDC28 Protein Kinase, S cerevisiaeCLB6 protein, S cerevisiaeCyclin BRibonucleoside Diphosphate ReductaseRibonucleotide ReductasesRNR2 protein, S cerevisiaeRnr4 protein, S cerevisiaeSaccharomyces cerevisiae Proteinscyclin-dependent kinasescyclinsdeoxyribonucleotidesnucleocytoplasmic transportribonucleotide reductaseS phase

Identifiers

PMID29263158
PMCPMC5829487
OpenAlexW2777927478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.