Evidence map›Paper›PMID 29263109›Full record

ArticleInfection and immunity2018

Prevalence of IgG and Neutralizing Antibodies against Staphylococcus aureus Alpha-Toxin in Healthy Human Subjects and Diverse Patient Populations.

Yuling Wu, Xu Liu, Ahmad Akhgar, Jia J Li, Hoyin Mok, Bret R Sellman, Li Yu, Lorin K Roskos, Mark T Esser, Alexey Ruzin

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Conserved CD4Nature microbiology · 2026
    Article
  3. Article
  4. LinkingAntibiotics (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Anti-Alpha-Toxin Antibody Responses and Clinical Outcomes ofJournal of Korean medical science · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Evasion of Immunological Memory byFrontiers in immunology · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. The Role of Macrophages inFrontiers in immunology · 2020
    Review
  18. Review
  19. Monoclonal antibody-based therapies for bacterial infections.Current opinion in infectious diseases · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuling WuClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Gaithersburg, Maryland, USA.
Xu LiuClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Gaithersburg, Maryland, USA.
Ahmad AkhgarClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Gaithersburg, Maryland, USA.
Jia J LiClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Gaithersburg, Maryland, USA.
Hoyin MokClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Mountain View, California, USA.
Bret R SellmanInfectious Disease Research, MedImmune, Gaithersburg, Maryland, USA.
Li YuStatistical Sciences, MedImmune, Gaithersburg, Maryland, USA.
Lorin K RoskosClinical Pharmacology and Drug Metabolism/Pharmacokinetics, MedImmune, Gaithersburg, Maryland, USA.
Mark T EsserInfectious Disease/Vaccines Translational Medicine, MedImmune, Gaithersburg, Maryland, USA.
Alexey RuzinInfectious Disease/Vaccines Translational Medicine, MedImmune, Gaithersburg, Maryland, USA ruzina@medimmune.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAgedAntibodies, BacterialAntibodies, NeutralizingBacterial ToxinsChildChild, PreschoolEnzyme-Linked Immunosorbent AssayFemaleHealthy VolunteersHemolysin ProteinsHumansImmunoglobulin GInfantMaleAntibodies, BacterialAntibodies, NeutralizingBacterial ToxinsHemolysin ProteinsImmunoglobulin Gstaphylococcal alpha-toxinalpha-toxinhuman subjectsserum antibodiesStaphylococcus aureus

Identifiers

PMID29263109
PMCPMC5820940
OpenAlexW2779429977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.