Evidence map›Paper›PMID 29263108›Full record

ArticleInfection and immunity2018

Evaluation of Protective Efficacy of Selected Immunodominant B-Cell Epitopes within Virulent Surface Proteins of Streptococcus pneumoniae.

Theodora Papastamatiou, John G Routsias, Olga Koutsoni, Eleni Dotsika, Athanassios Tsakris, Vana Spoulou

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Differences in Pneumococcal andFrontiers in immunology · 2021
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Diverse Mechanisms of Protective Anti-Pneumococcal Antibodies.Frontiers in cellular and infection microbiology · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Theodora Papastamatiou *1 Department of Paediatrics, Aghia Sophia Children's Hospital and Immunobiology and Vaccinology Research Laboratory, Athens, Greece.
John G Routsias *Department of Microbiology, National and Kapodistrian, University of Athens, Athens, Greece jroutsias@med.uoa.gr.
Olga KoutsoniLaboratory of Cellular Immunology, Hellenic Pasteur Institute, Athens, Greece.
Eleni DotsikaLaboratory of Cellular Immunology, Hellenic Pasteur Institute, Athens, Greece.
Athanassios TsakrisDepartment of Microbiology, National and Kapodistrian, University of Athens, Athens, Greece.
Vana Spoulou1 Department of Paediatrics, Aghia Sophia Children's Hospital and Immunobiology and Vaccinology Research Laboratory, Athens, Greece.
Children's Hospital Agia Sophia · GRNational and Kapodistrian University of Athens · GRPasteur Hellenic Institute · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four previously identified immunodominant B-cell epitopes, located within known virulent pneumococcal proteins CbpD, PhtD, PhtE, and ZmpB, had shown promising

Indexed as

AnimalsAntibodies, BacterialBacterial ProteinsDrug Evaluation, PreclinicalEpitopes, B-LymphocyteFemaleHumansImmunizationImmunodominant EpitopesMembrane ProteinsMiceMice, Inbred BALB CPneumococcal InfectionsStreptococcus pneumoniaeAntibodies, BacterialBacterial ProteinsEpitopes, B-LymphocyteImmunodominant EpitopesMembrane Proteinsanimal modelsB-cell epitopesOPKAS. pneumoniaesynthetic peptidesvaccine development

Identifiers

PMID29263108
PMCPMC5820952
OpenAlexW2779761385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.