Evidence map›Paper›PMID 29263105›Full record

ArticleInfection and immunity2018

Autoimmune-Disease-Prone NOD Mice Help To Reveal a New Genetic Locus for Reducing Pulmonary Disease Caused by Mycoplasma pulmonis.

Nadeeka K Wawegama, Philip F Markham, Colleen M Elso, Anna Kanci, Marc S Marenda, Glenn F Browning, Thomas C Brodnicki

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nadeeka K WawegamaAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria and Werribee, Victoria, Australia.
Philip F MarkhamAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria and Werribee, Victoria, Australia.
Colleen M ElsoSt. Vincent's Institute and Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Fitzroy, Victoria, Australia.
Anna KanciAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria and Werribee, Victoria, Australia.
Marc S MarendaAsia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria and Werribee, Victoria, Australia.
Glenn F Browning *Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria and Werribee, Victoria, Australia glenfb@unimelb.edu.au tbrodnicki@svi.edu.au.ORCID https://orcid.org/0000-0002-0903-2469
Thomas C Brodnicki *St. Vincent's Institute and Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Fitzroy, Victoria, Australia glenfb@unimelb.edu.au tbrodnicki@svi.edu.au.ORCID https://orcid.org/0000-0003-2294-315X
The University of Melbourne · AUSt Vincent's Hospital Melbourne · AU

Funding

Identification of Mouse Diabetes Susceptibility GenesR01DK062882 · NIDDK · WALTER AND ELIZA HALL INST MEDICAL RES · PI BRODNICKI, THOMAS C · 2005 to 2009
$796k
NIDDK NIH HHS R01 DK062882
6 · The paper itself

Abstract

Mycoplasmas are bacterial pathogens of a range of animals, including humans, and are a common cause of respiratory disease. However, the host genetic factors that affect resistance to infection or regulate the resulting pulmonary inflammation are not well defined. We and others have previously demonstrated that nonobese diabetic (NOD) mice can be used to investigate disease loci that affect bacterial infection and autoimmune diabetes. Here we show that NOD mice are more susceptible than C57BL/6 (B6) mice to infection with

Indexed as

Genetic Predisposition to DiseaseAnimalsAutoimmune DiseasesFemaleGenetic LociHumansLungMaleMiceMice, Inbred C57BLMice, Inbred NODMycoplasma InfectionsMycoplasma pulmonisautoimmune diseasecomplex genetic traitcongenic miceinfectious diseasemurine respiratory mycoplasmosisMycoplasma pulmonisnonobese diabetic mousepulmonary inflammationresistance loci

Identifiers

PMID29263105
PMCPMC5820957
OpenAlexW2779636996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.