Evidence map›Paper›PMID 29263093›Full record

ArticleThe Journal of biological chemistry2018

Silencing steroid receptor coactivator-1 in the nucleus of the solitary tract reduces estrogenic effects on feeding and apolipoprotein A-IV expression.

Ling Shen, Yin Liu, Patrick Tso, David Q-H Wang, W Sean Davidson, Stephen C Woods, Min Liu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Transport functions of intestinal lymphatic vessels.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Sex-steroid-dependent plasticity of brain-stem autonomic circuits.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Review
  10. GABAJournal of neurophysiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ling ShenFrom the Departments of Pathology and Laboratory Medicine and.
Yin LiuFrom the Departments of Pathology and Laboratory Medicine and.
Patrick TsoFrom the Departments of Pathology and Laboratory Medicine and.
David Q-H Wangthe Department of Medicine, Division of Gastroenterology and Liver Diseases, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York 10461.
W Sean DavidsonFrom the Departments of Pathology and Laboratory Medicine and.
Stephen C WoodsPsychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237 and.
Min LiuFrom the Departments of Pathology and Laboratory Medicine and lium@uc.edu.
University of Cincinnati · USAlbert Einstein College of Medicine · USUniversity of Cincinnati Medical Center · US

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
Special Animal CoreP30DK041296 · NIDDK · YESHIVA UNIVERSITY · PI GUPTA, SANJEEV · 1989 to 2018
$22.9M
Lipid profile, lipoprotein and apolipoprotein composition, and intestinal fat absorption efficiency in germ-free and conventional miceU2CDK059630 · NIDDK · UNIVERSITY OF CINCINNATI · PI LIU, MIN · 2016 to 2021
$4.9M
Role of the GI lymphatic system in hormonal signaling and nutrient metabolismR01DK119135 · NIDDK · UNIVERSITY OF CINCINNATI · PI LIU, MIN, TSO, PATRICK · 2018 to 2022
$3.0M
The therapeutic potential of smarter exosomes derived from engineered MSCs on Alzheimer's diseaseR01HL140962 · NHLBI · UNIVERSITY OF CINCINNATI · PI LIU, MIN, XU, MEIFENG · 2018 to 2021
$2.4M
Apolipoprotein AV and intestinal transportR01DK103557 · NIDDK · UNIVERSITY OF CINCINNATI · PI TSO, PATRICK · 2015 to 2019
$1.9M
Brain apoA-IV Mediates Estrogenic Reduction of Dietary Obesity in Female RatsR01DK092779 · NIDDK · UNIVERSITY OF CINCINNATI · PI LIU, MIN, WOODS, STEPHEN C · 2011 to 2015
$1.8M
Ginsenocide Rb1: A Novel Anti-Obesity and Anti-Hyperglycemic CompoundR01DK095440 · NIDDK · UNIVERSITY OF CINCINNATI · PI LIU, MIN, WOODS, STEPHEN C · 2012 to 2016
$1.6M
Apolipoprotein A5 and Gallstone FormationR01DK114516 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WANG, DAVID Q · 2018 to 2021
$1.5M
Gene therapy of alcoholic liver diseaseR21AA025737 · NIAAA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WANG, DAVID Q · 2017 to 2018
$438k
NHLBI NIH HHS R01 HL140962NIAAA NIH HHS R21 AA025737NIDDK NIH HHS P30 DK041296NIDDK NIH HHS P30 DK078392NIDDK NIH HHS R01 DK092779NIDDK NIH HHS R01 DK095440NIDDK NIH HHS R01 DK103557NIDDK NIH HHS R01 DK114516NIDDK NIH HHS R01 DK119135NIDDK NIH HHS U2C DK059630
6 · The paper itself

Abstract

We previously found that 17β-estradiol (E2) stimulates

Indexed as

AnimalsApolipoproteins ADiet, High-FatEatingEstradiolEstrogensFemaleGene SilencingHumansNuclear Receptor Coactivator 1ObesityOvariectomyRatsRats, Long-EvansSolitary Nucleusapolipoprotein A-IVApolipoproteins AEstradiolEstrogensNuclear Receptor Coactivator 1apolipoproteinenergy metabolismestrogenestrogen receptorobesitysmall interfering RNA (siRNA)

Identifiers

PMID29263093
PMCPMC5808769
OpenAlexW2780353862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.