ArticleJournal of the American Heart Association2017
Marital Status and Outcomes in Patients With Cardiovascular Disease.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 109 citations in OpenAlex.
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- Association between marital status and mortality risk in cardiac disease: a cardiopulmonary exercise testing cohort study.Environmental health and preventive medicine · 2026Observational
- Patient-reported outcomes and perceived medication confidence as predictors of healthcare utilization among adults with cardiovascular risk factors.Scientific reports · 2025Article
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- Additive interactions of smoking with obesity on ischemic heart disease mortality: a national prospective cohort study in the United States.International journal of epidemiology · 2025Article
- The impact of marital status on hypertension: SEM analysis of a Chinese general population cohort.BMC public health · 2025Article
- Analysis of Frailty Indices Based on Sociodemographic and Clinical Determinants in Older Women.Healthcare (Basel, Switzerland) · 2025Article
- Marriage is associated with decreased lesion volumes and less brain atrophy in people with multiple sclerosis.Journal of neurology · 2025Article
- Trajectories of health conditions predict cardiovascular disease risk among middle-aged and older adults: a national cohort study.Frontiers in nutrition · 2025Article
- Marital status and long-term cardiovascular risk in general population-RIFLE project (Italy).Irish journal of medical science · 2024Article
- Association of marital status with cardiovascular death risk in patients with lung cancer: A population-based study.Preventive medicine reports · 2024Article
- Association between the use of electronic cigarettes and myocardial infarction in U.S. adults.BMC public health · 2024Article
- Cardiovascular Disease and Stroke Risk Among Egyptian Resident Physicians: A Cross-Sectional Multicenter Study.Cureus · 2024Article
- Association between long-term exposure to PMFrontiers in public health · 2024Article
- Article
- Race, Social Determinants of Health, and Comorbidity Patterns Among Participants with Heart Failure in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.Discover social science and health · 2024Article
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundBeing unmarried is associated with decreased survival in the general population. Whether married, divorced, separated, widowed, or never-married status affects outcomes in patients with cardiovascular disease has not been well characterized. METHODS AND
resultsA prospective cohort (inception period 2003-2015) of 6051 patients (mean age 63 years, 64% male, 23% black) undergoing cardiac catheterization for suspected or confirmed coronary artery disease was followed for a median of 3.7 years (interquartile range: 1.7-6.7 years). Marital status was stratified as married (n=4088) versus unmarried (n=1963), which included those who were never married (n=451), divorced or separated (n=842), or widowed (n=670). The relationship between marital status and primary outcome of cardiovascular death and myocardial infarction was examined using Cox regression models adjusted for clinical characteristics. There were 1085 (18%) deaths from all causes, 688 (11%) cardiovascular-related deaths, and 272 (4.5%) incident myocardial infarction events. Compared with married participants, being unmarried was associated with higher risk of all-cause mortality (hazard ratio [HR]: 1.24; 95% confidence interval [CI], 1.06-1.47), cardiovascular death (HR: 1.45; 95% CI, 1.18-1.78), and cardiovascular death or myocardial infarction (HR: 1.52; 95% CI, 1.27-1.83). Compared with married participants, the increase in cardiovascular death or myocardial infarction was similar for the participants who were divorced or separated (HR: 1.41; 95% CI, 1.10-1.81), widowed (HR: 1.71; 95% CI, 1.32-2.20), or never married (HR: 1.40; 95% CI, 0.97-2.03). The findings persisted after adjustment for medications and other socioeconomic factors.
conclusionsMarital status is independently associated with cardiovascular outcomes in patients with or at high risk of cardiovascular disease, with higher mortality in the unmarried population. The mechanisms responsible for this increased risk require further study.
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